Eukaryotic Initiation Factor-4F
"Eukaryotic Initiation Factor-4F" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trimeric peptide initiation factor complex that associates with the 5' MRNA cap structure of RNA (RNA CAPS) and plays an essential role in MRNA TRANSLATION. It is composed of EUKARYOTIC INITIATION FACTOR-4A; EUKARYOTIC INITIATION FACTOR-4E; and EUKARYOTIC INITIATION FACTOR-4G.
Descriptor ID |
D039562
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MeSH Number(s) |
D12.776.664.962.750.374 D12.776.835.725.868.500
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Concept/Terms |
Eukaryotic Initiation Factor-4F- Eukaryotic Initiation Factor-4F
- Eukaryotic Initiation Factor 4F
- Initiation Factor-4F, Eukaryotic
- Protein Initiation Factor EIF-4F
- Protein Initiation Factor EIF 4F
- EIF4F Translation Initiation Complex
- Peptide Initiation Factor EIF-4F
- Peptide Initiation Factor EIF 4F
- EIF-4F
- EIF 4F
- EIF4F
EIF-(iso)4F- EIF-(iso)4F
- Eukaryotic Initiation Factor-(iso)4F
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Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-4F".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-4F".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-4F" by people in this website by year, and whether "Eukaryotic Initiation Factor-4F" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2007 | 1 | 1 | 2 |
2010 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-4F" by people in Profiles.
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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site. Cell Rep. 2021 11 02; 37(5):109934.
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Translational control mechanisms in long-lasting synaptic plasticity and memory. J Biol Chem. 2010 Oct 15; 285(42):31913-7.
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Amino acid availability and age affect the leucine stimulation of protein synthesis and eIF4F formation in muscle. Am J Physiol Endocrinol Metab. 2007 Dec; 293(6):E1615-21.
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Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiation. Am J Physiol Endocrinol Metab. 2007 Nov; 293(5):E1416-25.
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Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation. Mol Cell Biol. 2005 Dec; 25(23):10556-65.
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A novel interaction of Cap-binding protein complexes eukaryotic initiation factor (eIF) 4F and eIF(iso)4F with a region in the 3'-untranslated region of satellite tobacco necrosis virus. J Biol Chem. 2004 Apr 02; 279(14):13584-92.
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Regulation of translation initiation by insulin and amino acids in skeletal muscle of neonatal pigs. Am J Physiol Endocrinol Metab. 2003 Jul; 285(1):E40-53.
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Feeding stimulates protein synthesis in muscle and liver of neonatal pigs through an mTOR-dependent process. Am J Physiol Endocrinol Metab. 2000 Nov; 279(5):E1080-7.
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cDNA cloning, expression analysis, and chromosomal localization of a gene with high homology to wheat eIF-(iso)4F and mammalian eIF-4G. Genomics. 1997 Jan 15; 39(2):192-7.
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Persistent infection of human erythroblastoid cells by poliovirus. Virology. 1993 May; 194(1):200-9.