"Septins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of GTP-binding proteins that were initially identified in YEASTS where they were shown to initiate the process of septation and bud formation. Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act as cytoskeletal elements that play important roles in CYTOKINESIS, cytoskeletal reorganization, BIOLOGICAL TRANSPORT, and membrane dynamics.
| Descriptor ID |
D058112
|
| MeSH Number(s) |
D08.811.277.040.330.300.700 D12.776.157.325.757 D12.776.220.932
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Septins".
Below are MeSH descriptors whose meaning is more specific than "Septins".
This graph shows the total number of publications written about "Septins" by people in this website by year, and whether "Septins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Septins" by people in Profiles.
-
Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice. Nat Commun. 2023 07 25; 14(1):4101.
-
Sperm-borne miR-202 targets SEPT7 and regulates first cleavage of bovine embryos via cytoskeletal remodeling. Development. 2021 03 05; 148(5).
-
NCCN Guidelines Insights: Colorectal Cancer Screening, Version 1.2018. J Natl Compr Canc Netw. 2018 08; 16(8):939-949.
-
Folate-dependent methylation of septins governs ciliogenesis during neural tube closure. FASEB J. 2017 08; 31(8):3622-3635.
-
Non-recurrent SEPT9 duplications cause hereditary neuralgic amyotrophy. J Med Genet. 2010 Sep; 47(9):601-7.
-
Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins. J Neurosci Res. 2009 Nov 15; 87(15):3502-10.
-
SEPT9 gene sequencing analysis reveals recurrent mutations in hereditary neuralgic amyotrophy. Neurology. 2009 May 19; 72(20):1755-9.
-
Duplication within the SEPT9 gene associated with a founder effect in North American families with hereditary neuralgic amyotrophy. Hum Mol Genet. 2009 Apr 01; 18(7):1200-8.