"Sphingolipids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
| Descriptor ID |
D013107
|
| MeSH Number(s) |
D10.570.877
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sphingolipids".
Below are MeSH descriptors whose meaning is more specific than "Sphingolipids".
This graph shows the total number of publications written about "Sphingolipids" by people in this website by year, and whether "Sphingolipids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2016 | 3 | 1 | 4 |
| 2017 | 5 | 1 | 6 |
| 2018 | 2 | 2 | 4 |
| 2020 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sphingolipids" by people in Profiles.
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Drosophila models uncover substrate channeling effects on phospholipids and sphingolipids in peroxisomal biogenesis disorders. PLoS One. 2025; 20(6):e0324143.
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Amelioration of Fibrosis via S1P Inhibition Is Regulated by Inactivation of TGF-? and SPL Pathways in the Human Cornea. Int J Mol Sci. 2024 Jun 14; 25(12).
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Potentiation of Sphingolipids and TGF-? in the human corneal stroma reveals intricate signaling pathway crosstalks. Exp Eye Res. 2023 06; 231:109487.
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SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia. Brain. 2023 04 19; 146(4):1420-1435.
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Mucosal and Plasma Metabolomes in New-onset Paediatric Inflammatory Bowel Disease: Correlations with Disease Characteristics and Plasma Inflammation Protein Markers. J Crohns Colitis. 2023 Apr 03; 17(3):418-432.
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Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model. Cells. 2022 09 17; 11(18).
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Characterization of inositol lipid metabolism in gut-associated Bacteroidetes. Nat Microbiol. 2022 07; 7(7):986-1000.
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Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron. J Lipid Res. 2022 07; 63(7):100236.
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Host hepatic metabolism is modulated by gut microbiota-derived sphingolipids. Cell Host Microbe. 2022 06 08; 30(6):798-808.e7.
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The microbiome affects liver sphingolipids and plasma fatty acids in a murine model of the Western diet based on soybean oil. J Nutr Biochem. 2021 11; 97:108808.