"Sphingolipids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
| Descriptor ID |
D013107
|
| MeSH Number(s) |
D10.570.877
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sphingolipids".
Below are MeSH descriptors whose meaning is more specific than "Sphingolipids".
This graph shows the total number of publications written about "Sphingolipids" by people in this website by year, and whether "Sphingolipids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2016 | 3 | 0 | 3 |
| 2017 | 5 | 1 | 6 |
| 2018 | 2 | 2 | 4 |
| 2020 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sphingolipids" by people in Profiles.
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Drosophila models uncover substrate channeling effects on phospholipids and sphingolipids in peroxisomal biogenesis disorders. PLoS One. 2025; 20(6):e0324143.
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Amelioration of Fibrosis via S1P Inhibition Is Regulated by Inactivation of TGF-? and SPL Pathways in the Human Cornea. Int J Mol Sci. 2024 Jun 14; 25(12).
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SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia. Brain. 2023 04 19; 146(4):1420-1435.
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Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model. Cells. 2022 09 17; 11(18).
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Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer. Nat Commun. 2020 08 27; 11(1):4279.
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Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Am J Clin Nutr. 2020 07 01; 112(1):57-65.
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Respiratory viruses are associated with serum metabolome among infants hospitalized for bronchiolitis: A multicenter study. Pediatr Allergy Immunol. 2020 10; 31(7):755-766.
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Sphingolipids in the Pathogenesis of Parkinson's Disease and Parkinsonism. Trends Endocrinol Metab. 2019 02; 30(2):106-117.
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Drosophila DNA/RNA methyltransferase contributes to robust host defense in aging animals by regulating sphingolipid metabolism. J Exp Biol. 2018 11 16; 221(Pt 22).
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Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to a-Synuclein Gain. Cell Metab. 2018 10 02; 28(4):605-618.e6.