Fragile X Mental Retardation Protein
"Fragile X Mental Retardation Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A RNA-binding protein that is found predominately in the CYTOPLASM. It helps regulate GENETIC TRANSLATION in NEURONS and is absent or under-expressed in FRAGILE X SYNDROME.
| Descriptor ID |
D051860
|
| MeSH Number(s) |
D12.776.157.725.061 D12.776.631.299 D12.776.664.962.124
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fragile X Mental Retardation Protein".
Below are MeSH descriptors whose meaning is more specific than "Fragile X Mental Retardation Protein".
This graph shows the total number of publications written about "Fragile X Mental Retardation Protein" by people in this website by year, and whether "Fragile X Mental Retardation Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 5 | 5 |
| 1995 | 0 | 6 | 6 |
| 1996 | 0 | 4 | 4 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 4 | 4 |
| 2004 | 0 | 3 | 3 |
| 2005 | 2 | 2 | 4 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 2 | 3 |
| 2008 | 9 | 0 | 9 |
| 2009 | 6 | 2 | 8 |
| 2010 | 2 | 0 | 2 |
| 2011 | 5 | 3 | 8 |
| 2012 | 4 | 1 | 5 |
| 2014 | 3 | 2 | 5 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 1 | 4 |
| 2021 | 2 | 4 | 6 |
| 2022 | 1 | 3 | 4 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fragile X Mental Retardation Protein" by people in Profiles.
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Calcium-Dependent Regulation of Neuronal Excitability Is Rescued in Fragile X Syndrome by a Tat-Conjugated N-Terminal Fragment of FMRP. J Neurosci. 2024 May 22; 44(21).
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Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome. Neuron. 2023 10 04; 111(19):3028-3040.e6.
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The diagnostic experience of women with fragile X-associated primary ovarian insufficiency (FXPOI). J Assist Reprod Genet. 2023 Jan; 40(1):179-190.
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Descriptive analysis of seizures and comorbidities associated with fragile X syndrome. Mol Genet Genomic Med. 2022 08; 10(8):e2001.
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Identification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome. Proc Natl Acad Sci U S A. 2022 05 31; 119(22):e2118124119.
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Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression. EMBO Mol Med. 2022 04 07; 14(4):e15344.
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Dietary rescue of adult behavioral deficits in the Fmr1 knockout mouse. PLoS One. 2022; 17(1):e0262916.
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Functional consequences of postnatal interventions in a mouse model of Fragile X syndrome. Neurobiol Dis. 2022 01; 162:105577.
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Genetic insights into biological mechanisms governing human ovarian ageing. Nature. 2021 08; 596(7872):393-397.
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Simultaneous Screening of the FRAXA and FRAXE Loci for Rapid Detection of FMR1 CGG and/or AFF2 CCG Repeat Expansions by Triplet-Primed PCR. J Mol Diagn. 2021 08; 23(8):941-951.