"Calcium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.
| Descriptor ID |
D015220
|
| MeSH Number(s) |
D12.776.157.530.400.150 D12.776.543.550.450.150 D12.776.543.585.400.150
|
| Concept/Terms |
Calcium Channels- Calcium Channels
- Ion Channel, Calcium
- Calcium Ion Channel
- Ion Channels, Calcium
- Calcium Ion Channels
- Calcium Channel Blocker Receptor
- VDCC
- Receptors, Calcium Channel Blocker
- Calcium Channel Antagonist Receptors
- Receptors, Calcium Channel Antagonist
- Calcium Channel Antagonist Receptor
- Voltage-Dependent Calcium Channels
- Calcium Channels, Voltage-Dependent
- Channels, Voltage-Dependent Calcium
- Voltage Dependent Calcium Channels
- Calcium Channel
- Calcium Channel Blocker Receptors
|
Below are MeSH descriptors whose meaning is more general than "Calcium Channels".
Below are MeSH descriptors whose meaning is more specific than "Calcium Channels".
This graph shows the total number of publications written about "Calcium Channels" by people in this website by year, and whether "Calcium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 |
| 1995 | 5 | 2 | 7 |
| 1996 | 6 | 2 | 8 |
| 1997 | 8 | 3 | 11 |
| 1998 | 3 | 2 | 5 |
| 1999 | 8 | 3 | 11 |
| 2000 | 5 | 4 | 9 |
| 2001 | 5 | 4 | 9 |
| 2002 | 2 | 0 | 2 |
| 2003 | 3 | 2 | 5 |
| 2004 | 4 | 2 | 6 |
| 2005 | 2 | 2 | 4 |
| 2006 | 2 | 5 | 7 |
| 2007 | 4 | 2 | 6 |
| 2008 | 5 | 0 | 5 |
| 2009 | 3 | 3 | 6 |
| 2010 | 5 | 0 | 5 |
| 2011 | 2 | 3 | 5 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 3 | 1 | 4 |
| 2017 | 3 | 3 | 6 |
| 2018 | 2 | 3 | 5 |
| 2019 | 2 | 2 | 4 |
| 2020 | 2 | 2 | 4 |
| 2021 | 0 | 2 | 2 |
| 2022 | 3 | 2 | 5 |
| 2023 | 0 | 2 | 2 |
| 2024 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Calcium Channels" by people in Profiles.
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MCU-independent Ca2+ uptake mediates mitochondrial Ca2+ overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy. Sci Rep. 2024 03 21; 14(1):6751.
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Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation. J Clin Invest. 2024 Jan 02; 134(1).
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Pearls & Oy-sters: CACNA1A-Related Paroxysmal Tonic Upgaze With Ataxia Responsive to Acetazolamide. Neurology. 2024 Jan 09; 102(1):e207992.
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MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle. Cell Rep. 2023 11 28; 42(11):113465.
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Biallelic CACNA2D1 loss-of-function variants cause early-onset developmental epileptic encephalopathy. Brain. 2022 08 27; 145(8):2721-2729.
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Two-pore channel blockade by phosphoinositide kinase inhibitors YM201636 and PI-103 determined by a histidine residue near pore-entrance. Commun Biol. 2022 07 23; 5(1):738.
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Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer. Cancer Res. 2022 06 15; 82(12):2254-2268.
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Complex effects on CaV2.1 channel gating caused by a CACNA1A variant associated with a severe neurodevelopmental disorder. Sci Rep. 2022 06 02; 12(1):9186.
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Diversity of two-pore channels and the accessory NAADP receptors in intracellular Ca2+ signaling. Cell Calcium. 2022 06; 104:102594.
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Lsm12 is an NAADP receptor and a two-pore channel regulatory protein required for calcium mobilization from acidic organelles. Nat Commun. 2021 08 06; 12(1):4739.