"Glioblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Descriptor ID |
D005909
|
| MeSH Number(s) |
C04.557.465.625.600.380.080.335 C04.557.470.670.380.080.335 C04.557.580.625.600.380.080.335
|
| Concept/Terms |
Glioblastoma- Glioblastoma
- Glioblastomas
- Astrocytoma, Grade IV
- Astrocytomas, Grade IV
- Grade IV Astrocytoma
- Grade IV Astrocytomas
Giant Cell Glioblastoma- Giant Cell Glioblastoma
- Giant Cell Glioblastomas
- Glioblastoma, Giant Cell
- Glioblastomas, Giant Cell
|
Below are MeSH descriptors whose meaning is more general than "Glioblastoma".
Below are MeSH descriptors whose meaning is more specific than "Glioblastoma".
This graph shows the total number of publications written about "Glioblastoma" by people in this website by year, and whether "Glioblastoma" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 1 | 3 | 4 |
| 1997 | 1 | 1 | 2 |
| 1998 | 2 | 1 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 4 | 0 | 4 |
| 2004 | 1 | 0 | 1 |
| 2005 | 3 | 1 | 4 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 1 | 3 |
| 2008 | 4 | 1 | 5 |
| 2009 | 3 | 1 | 4 |
| 2010 | 10 | 2 | 12 |
| 2011 | 3 | 5 | 8 |
| 2012 | 12 | 0 | 12 |
| 2013 | 8 | 4 | 12 |
| 2014 | 14 | 1 | 15 |
| 2015 | 12 | 4 | 16 |
| 2016 | 8 | 1 | 9 |
| 2017 | 16 | 0 | 16 |
| 2018 | 14 | 1 | 15 |
| 2019 | 14 | 1 | 15 |
| 2020 | 10 | 2 | 12 |
| 2021 | 12 | 0 | 12 |
| 2022 | 10 | 0 | 10 |
| 2023 | 17 | 1 | 18 |
| 2024 | 15 | 0 | 15 |
| 2025 | 11 | 0 | 11 |
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Below are the most recent publications written about "Glioblastoma" by people in Profiles.
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Phase 2 trial of personal dendritic cell vaccines in newly diagnosed glioblastoma: 3-year follow-up and correlations with survival. Hum Vaccin Immunother. 2025 Dec; 21(1):2556591.
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Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions. Nature. 2025 Aug; 644(8078):1097-1106.
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Molecular and clinical determinants of response to checkpoint inhibitor immunotherapy in glioblastoma. J Neurooncol. 2025 Oct; 175(1):453-461.
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DNA-PK Inhibition Shows Differential Radiosensitization in Orthotopic GBM PDX Models Based on DDR Pathway Deficits. Mol Cancer Ther. 2025 Jun 04; 24(6):859-869.
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NLRP3 Inflammasome Activation Expands the Immunosuppressive Myeloid Stroma and Antagonizes the Therapeutic Benefit of STING Activation in Glioblastoma. Cancer Res Commun. 2025 Jun 01; 5(6):960-972.
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Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity. Nature. 2025 Jul; 643(8070):219-229.
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Machine learning-based prognostic subgrouping of glioblastoma: A multicenter study. Neuro Oncol. 2025 May 15; 27(4):1102-1115.
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Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression. Nat Commun. 2025 Mar 26; 16(1):2974.
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Clinical and genetic markers of vascular toxicity in glioblastoma patients: Insights from NRG Oncology RTOG-0825. Neuro Oncol. 2025 Mar 07; 27(3):767-778.
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MGMT epimutations and risk of incident cancer of the colon, glioblastoma multiforme, and diffuse large B cell lymphomas. Clin Epigenetics. 2025 Feb 20; 17(1):28.