"Receptor, EphB4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eph family receptor found in a variety of adult and embryonic tissues. Unlike the majority of proteins in this class there is little or no expression of EphB4 receptor in the BRAIN. It has been found at high levels in developing mammary glands and in invasive mammary tumors.
Descriptor ID |
D036224
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MeSH Number(s) |
D08.811.913.696.620.682.725.400.850.750 D12.776.543.750.630.500.781
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Concept/Terms |
Receptor, EphB4- Receptor, EphB4
- EPHB4 Protein
- Hepatoma Transmembrane Kinase
- Kinase, Hepatoma Transmembrane
- Transmembrane Kinase, Hepatoma
- EphB4 Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptor, EphB4".
Below are MeSH descriptors whose meaning is more specific than "Receptor, EphB4".
This graph shows the total number of publications written about "Receptor, EphB4" by people in this website by year, and whether "Receptor, EphB4" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2010 | 2 | 0 | 2 |
2011 | 2 | 0 | 2 |
2012 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, EphB4" by people in Profiles.
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Targeting Forward and Reverse EphB4/EFNB2 Signaling by a Peptide with Dual Functions. Sci Rep. 2020 01 16; 10(1):520.
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Germline Loss-of-Function Mutations in EPHB4 Cause a Second Form of Capillary Malformation-Arteriovenous Malformation (CM-AVM2) Deregulating RAS-MAPK Signaling. Circulation. 2017 Sep 12; 136(11):1037-1048.
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Erythropoietin Stimulates Tumor Growth via EphB4. Cancer Cell. 2015 Nov 09; 28(5):610-622.
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Dual-modality micro-positron emission tomography/computed tomography and near-infrared fluorescence imaging of EphB4 in orthotopic glioblastoma xenograft models. Mol Imaging Biol. 2014 Feb; 16(1):74-84.
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Specific tumor delivery of paclitaxel using glycolipid-like polymer micelles containing gold nanospheres. Biomaterials. 2013 Jun; 34(18):4510-9.
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Effective photothermal chemotherapy using doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res. 2012 Sep 15; 72(18):4777-86.
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Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts. Biomaterials. 2011 Sep; 32(25):5872-9.
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In vivo small-animal PET/CT of EphB4 receptors using 64Cu-labeled peptide. J Nucl Med. 2011 Feb; 52(2):241-8.
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Converging evidence for efficacy from parallel EphB4-targeted approaches in ovarian carcinoma. Mol Cancer Ther. 2010 Aug; 9(8):2377-88.
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Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia. Blood. 2010 Mar 25; 115(12):2412-9.