"Necator americanus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A common parasite of humans in the moist tropics and subtropics. These organisms attach to villi in the small intestine and suck blood causing diarrhea, anorexia, and anemia.
| Descriptor ID |
D017221
|
| MeSH Number(s) |
B01.050.500.500.294.400.968.100.550.100
|
| Concept/Terms |
Necator americanus- Necator americanus
- Hookworm, New World
- Hookworms, New World
- New World Hookworm
- New World Hookworms
|
Below are MeSH descriptors whose meaning is more general than "Necator americanus".
Below are MeSH descriptors whose meaning is more specific than "Necator americanus".
This graph shows the total number of publications written about "Necator americanus" by people in this website by year, and whether "Necator americanus" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 3 | 1 | 4 |
| 2000 | 2 | 0 | 2 |
| 2001 | 3 | 0 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 3 | 0 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 6 | 0 | 6 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 3 | 1 | 4 |
| 2009 | 2 | 0 | 2 |
| 2010 | 4 | 1 | 5 |
| 2011 | 1 | 1 | 2 |
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2024 | 3 | 0 | 3 |
| 2025 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Necator americanus" by people in Profiles.
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Proteomic characterization and comparison of the infective and adult life stage secretomes from Necator americanus and Ancylostoma ceylanicum. PLoS Negl Trop Dis. 2025 Jan; 19(1):e0012780.
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Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. PLoS Negl Trop Dis. 2025 Jan; 19(1):e0012809.
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Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-na?ve adults. PLoS Negl Trop Dis. 2024 Dec; 18(12):e0012788.
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Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, phase 1, dose-escalation trial. Lancet Infect Dis. 2024 Jul; 24(7):760-774.
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Controlled Infection of Humans with the Hookworm Parasite Necator americanus to Accelerate Vaccine Development : The Human Hookworm Vaccination/Challenge Model (HVCM). Curr Top Microbiol Immunol. 2024; 445:367-377.
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Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial. Lancet Infect Dis. 2021 02; 21(2):275-285.
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Bacillus thuringiensis Cry5B protein as a new pan-hookworm cure. Int J Parasitol Drugs Drug Resist. 2018 08; 8(2):287-294.
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A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development. PLoS Pathog. 2018 03; 14(3):e1006931.
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Human Intestinal Parasite Burden and Poor Sanitation in Rural Alabama. Am J Trop Med Hyg. 2017 Nov; 97(5):1623-1628.
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Hookworm infection. Nat Rev Dis Primers. 2016 12 08; 2:16088.