CARD Signaling Adaptor Proteins
"CARD Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of intracellular signaling adaptor proteins that contain CASPASE ACTIVATION AND RECRUITMENT DOMAINS (CARD). They play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.
| Descriptor ID |
D053468
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| MeSH Number(s) |
D12.644.360.024.131 D12.644.360.075.358 D12.776.157.057.006 D12.776.476.024.139 D12.776.476.075.358
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "CARD Signaling Adaptor Proteins".
Below are MeSH descriptors whose meaning is more specific than "CARD Signaling Adaptor Proteins".
This graph shows the total number of publications written about "CARD Signaling Adaptor Proteins" by people in this website by year, and whether "CARD Signaling Adaptor Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 4 | 5 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 5 | 5 |
| 2015 | 3 | 1 | 4 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 2 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "CARD Signaling Adaptor Proteins" by people in Profiles.
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Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses. Cell Rep. 2024 03 26; 43(3):113944.
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Dectin-1/CARD9 induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-Aspergillus activity in the lung. Infect Immun. 2023 11 16; 91(11):e0021723.
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Rare variant associations with plasma protein levels in the UK Biobank. Nature. 2023 10; 622(7982):339-347.
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CARD19 Interacts with Mitochondrial Contact Site and Cristae Organizing System Constituent Proteins and Regulates Cristae Morphology. Cells. 2022 03 31; 11(7).
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CARD9 Expression Pattern, Gene Dosage, and Immunodeficiency Phenotype Revisited. J Clin Immunol. 2022 02; 42(2):336-349.
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Identification of a genetic signature enriching for response to ibrutinib in relapsed/refractory follicular lymphoma in the DAWN phase 2 trial. Cancer Med. 2022 01; 11(1):61-73.
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Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection. PLoS Pathog. 2021 10; 17(10):e1009967.
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Fungal cutaneous microbiome and host determinants in preterm and term neonates. Pediatr Res. 2020 08; 88(2):225-233.
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Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease. J Allergy Clin Immunol. 2019 04; 143(4):1482-1495.
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NLRC4 inflammasomopathies. Curr Opin Allergy Clin Immunol. 2017 Dec; 17(6):398-404.