CARD Signaling Adaptor Proteins
"CARD Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of intracellular signaling adaptor proteins that contain CASPASE ACTIVATION AND RECRUITMENT DOMAINS (CARD). They play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.
| Descriptor ID |
D053468
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| MeSH Number(s) |
D12.644.360.024.131 D12.644.360.075.358 D12.776.157.057.006 D12.776.476.024.139 D12.776.476.075.358
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "CARD Signaling Adaptor Proteins".
Below are MeSH descriptors whose meaning is more specific than "CARD Signaling Adaptor Proteins".
This graph shows the total number of publications written about "CARD Signaling Adaptor Proteins" by people in this website by year, and whether "CARD Signaling Adaptor Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 4 | 5 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 5 | 5 |
| 2015 | 3 | 1 | 4 |
| 2016 | 0 | 1 | 1 |
| 2017 | 4 | 2 | 6 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 2 | 2 | 4 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "CARD Signaling Adaptor Proteins" by people in Profiles.
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Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses. Cell Rep. 2024 03 26; 43(3):113944.
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Pityriasis Rubra Pilaris: An Updated Review of Clinical Presentation, Etiopathogenesis, and Treatment Options. Am J Clin Dermatol. 2024 Mar; 25(2):243-259.
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CARD19 Interacts with Mitochondrial Contact Site and Cristae Organizing System Constituent Proteins and Regulates Cristae Morphology. Cells. 2022 03 31; 11(7).
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CARD9 Expression Pattern, Gene Dosage, and Immunodeficiency Phenotype Revisited. J Clin Immunol. 2022 02; 42(2):336-349.
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Identification of a genetic signature enriching for response to ibrutinib in relapsed/refractory follicular lymphoma in the DAWN phase 2 trial. Cancer Med. 2022 01; 11(1):61-73.
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Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination. Cell Rep. 2021 10 26; 37(4):109904.
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Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection. PLoS Pathog. 2021 10; 17(10):e1009967.
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Gene Body Methylation of the Lymphocyte-Specific Gene CARD11 Results in Its Overexpression and Regulates Cancer mTOR Signaling. Mol Cancer Res. 2021 11; 19(11):1917-1928.
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A Novel Mutation in the NBD Domain of NLRC4 Causes Mild Autoinflammation With Recurrent Urticaria. Front Immunol. 2021; 12:674808.
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Resistance Mutations to BTK Inhibitors Originate From the NF-?B but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway. Front Immunol. 2021; 12:689472.