Nod1 Signaling Adaptor Protein
"Nod1 Signaling Adaptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.
| Descriptor ID |
D053474
|
| MeSH Number(s) |
D12.644.360.024.131.249 D12.644.360.024.313.249 D12.644.360.075.358.249 D12.644.360.539.500.249 D12.776.157.057.006.249 D12.776.157.057.078.249 D12.776.476.024.139.249 D12.776.476.024.391.249 D12.776.476.075.358.249
|
| Concept/Terms |
Nod1 Signaling Adaptor Protein- Nod1 Signaling Adaptor Protein
- Caspase Recruitment Domain Protein 4
- Nucleotide Oligomerization Domain 1 Protein
- CARD4 Protein
|
Below are MeSH descriptors whose meaning is more general than "Nod1 Signaling Adaptor Protein".
Below are MeSH descriptors whose meaning is more specific than "Nod1 Signaling Adaptor Protein".
This graph shows the total number of publications written about "Nod1 Signaling Adaptor Protein" by people in this website by year, and whether "Nod1 Signaling Adaptor Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nod1 Signaling Adaptor Protein" by people in Profiles.
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Hematopoiesis and the bacterial microbiome. Blood. 2018 08 09; 132(6):559-564.
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Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors. Chem Biol. 2015 Sep 17; 22(9):1174-84.