"U937 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A human cell line established from a diffuse histiocytic lymphoma (HISTIOCYTIC LYMPHOMA, DIFFUSE) and displaying many monocytic characteristics. It serves as an in vitro model for MONOCYTE and MACROPHAGE differentiation.
| Descriptor ID |
D020298
|
| MeSH Number(s) |
A11.251.210.190.880 A11.251.860.180.880 A11.627.482.665.500 A11.627.624.249.500 A11.627.635.675.750.500
|
| Concept/Terms |
U937 Cells- U937 Cells
- Cell, U937
- Cells, U937
- U937 Cell
|
Below are MeSH descriptors whose meaning is more general than "U937 Cells".
Below are MeSH descriptors whose meaning is more specific than "U937 Cells".
This graph shows the total number of publications written about "U937 Cells" by people in this website by year, and whether "U937 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 7 | 7 |
| 2000 | 1 | 5 | 6 |
| 2001 | 0 | 7 | 7 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 9 | 9 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 7 | 7 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 4 | 4 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 3 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 6 | 6 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "U937 Cells" by people in Profiles.
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The CD33 short isoform is a gain-of-function variant that enhances A?1-42 phagocytosis in microglia. Mol Neurodegener. 2021 03 25; 16(1):19.
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BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment. J Clin Invest. 2019 05 01; 129(5):1878-1894.
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The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability. Cancer Cell. 2018 11 12; 34(5):823-839.e7.
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Microscale Gene Expression Analysis of Tumor-Associated Macrophages. Sci Rep. 2018 02 05; 8(1):2408.
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JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. J Clin Invest. 2017 12 01; 127(12):4498-4515.
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PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4. Oncogene. 2017 08; 36(31):4481-4497.
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The Potent ALK Inhibitor Brigatinib (AP26113) Overcomes Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in Preclinical Models. Clin Cancer Res. 2016 Nov 15; 22(22):5527-5538.
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MLN0128, a novel mTOR kinase inhibitor, disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells. Oncotarget. 2016 Aug 23; 7(34):55083-55097.
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Biguanides sensitize leukemia cells to ABT-737-induced apoptosis by inhibiting mitochondrial electron transport. Oncotarget. 2016 Aug 09; 7(32):51435-51449.
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PR1-specific cytotoxic T lymphocytes are relatively frequent in umbilical cord blood and can be effectively expanded to target myeloid leukemia. Cytotherapy. 2016 08; 18(8):995-1001.