"THP-1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport.
| Descriptor ID |
D000074084
|
| MeSH Number(s) |
A11.251.210.190.815 A11.251.860.180.815
|
| Concept/Terms |
THP-1 Cells- THP-1 Cells
- Cell, THP-1
- Cells, THP-1
- THP 1 Cells
- THP-1 Cell
- THP-1 Cell Line
- Cell Line, THP-1
- Cell Lines, THP-1
- THP 1 Cell Line
- THP-1 Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "THP-1 Cells".
Below are MeSH descriptors whose meaning is more specific than "THP-1 Cells".
This graph shows the total number of publications written about "THP-1 Cells" by people in this website by year, and whether "THP-1 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 5 | 5 |
| 2019 | 0 | 4 | 4 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 5 | 5 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "THP-1 Cells" by people in Profiles.
-
IFN-treated macrophage-derived exosomes prevents HBV-HCC migration and invasion via regulating miR-106b-3p/PCGF3/PI3K/AKT signaling axis. Front Cell Infect Microbiol. 2024; 14:1421195.
-
A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. Cell Rep. 2021 08 24; 36(8):109576.
-
CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity. Blood. 2021 07 29; 138(4):318-330.
-
ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses. J Exp Med. 2021 09 06; 218(9).
-
lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms. JCI Insight. 2021 06 08; 6(11).
-
Identification of Inhibitors of Integrin Cytoplasmic Domain Interactions With Syk. Front Immunol. 2020; 11:575085.
-
M2-TAM subsets altered by lactic acid promote T-cell apoptosis through the PD-L1/PD-1 pathway. Oncol Rep. 2020 11; 44(5):1885-1894.
-
Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies. Cell Host Microbe. 2020 06 10; 27(6):976-991.e11.
-
Targeting the NLRP3 Inflammasome With Inhibitor MCC950 Prevents Aortic Aneurysms and Dissections in Mice. J Am Heart Assoc. 2020 04 07; 9(7):e014044.
-
Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization. Infect Immun. 2019 12; 87(12).