"THP-1 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A human leukemia monocytic cell line derived from a patient with LEUKEMIA, MONOCYTIC, ACUTE. It is used as a model to study the function of MONOCYTES and MACROPHAGES, their signaling pathways, nutrient and drug transport.
| Descriptor ID |
D000074084
|
| MeSH Number(s) |
A11.251.210.190.815 A11.251.860.180.815
|
| Concept/Terms |
THP-1 Cells- THP-1 Cells
- Cell, THP-1
- Cells, THP-1
- THP 1 Cells
- THP-1 Cell
- THP-1 Cell Line
- Cell Line, THP-1
- Cell Lines, THP-1
- THP 1 Cell Line
- THP-1 Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "THP-1 Cells".
Below are MeSH descriptors whose meaning is more specific than "THP-1 Cells".
This graph shows the total number of publications written about "THP-1 Cells" by people in this website by year, and whether "THP-1 Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 7 | 7 |
| 2019 | 0 | 8 | 8 |
| 2020 | 0 | 6 | 6 |
| 2021 | 0 | 7 | 7 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "THP-1 Cells" by people in Profiles.
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IFN-treated macrophage-derived exosomes prevents HBV-HCC migration and invasion via regulating miR-106b-3p/PCGF3/PI3K/AKT signaling axis. Front Cell Infect Microbiol. 2024; 14:1421195.
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A novel missense mutation in TNFAIP3 causes haploinsufficiency of A20. Cell Immunol. 2022 01; 371:104453.
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A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. Cell Rep. 2021 08 24; 36(8):109576.
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CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity. Blood. 2021 07 29; 138(4):318-330.
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ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses. J Exp Med. 2021 09 06; 218(9).
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Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker. Nat Cell Biol. 2021 06; 23(6):631-641.
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lncRNA DRAIR is downregulated in diabetic monocytes and modulates the inflammatory phenotype via epigenetic mechanisms. JCI Insight. 2021 06 08; 6(11).
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TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis. J Clin Invest. 2021 04 15; 131(8).
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Epac1 (Exchange Protein Directly Activated by cAMP 1) Upregulates LOX-1 (Oxidized Low-Density Lipoprotein Receptor 1) to Promote Foam Cell Formation and Atherosclerosis Development. Arterioscler Thromb Vasc Biol. 2020 12; 40(12):e322-e335.
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Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity. Front Immunol. 2020; 11:576310.