"PC12 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated with NERVE GROWTH FACTOR, making the line a useful model system for NERVE CELL differentiation.
| Descriptor ID |
D016716
|
| MeSH Number(s) |
A11.251.210.190.750 A11.251.860.180.750 A11.299.500
|
| Concept/Terms |
PC12 Cells- PC12 Cells
- PC12 Cell
- Pheochromocytoma Cell Line
- Cell Line, Pheochromocytoma
- Cell Lines, Pheochromocytoma
- Pheochromocytoma Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "PC12 Cells".
Below are MeSH descriptors whose meaning is more specific than "PC12 Cells".
This graph shows the total number of publications written about "PC12 Cells" by people in this website by year, and whether "PC12 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2008 | 1 | 2 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 3 | 3 |
| 2012 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "PC12 Cells" by people in Profiles.
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Structurally diverse chromane meroterpenoids from Rhododendron capitatum with multifunctional neuroprotective effects. Eur J Med Chem. 2025 Feb 05; 283:117188.
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Inflammatory neuronal loss in the substantia nigra induced by systemic lipopolysaccharide is prevented by knockout of the P2Y6 receptor in mice. J Neuroinflammation. 2021 Oct 11; 18(1):225.
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Cancer exosomes induce tumor innervation. Nat Commun. 2018 10 16; 9(1):4284.
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Secretome of Differentiated PC12 Cells Restores the Monocrotophos-Induced Damages in Human Mesenchymal Stem Cells and SHSY-5Y Cells: Role of Autophagy and Mitochondrial Dynamics. Neuromolecular Med. 2018 06; 20(2):233-251.
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Secretome of Differentiated PC12 Cells Enhances Neuronal Differentiation in Human Mesenchymal Stem Cells Via NGF-Like Mechanism. Mol Neurobiol. 2018 Nov; 55(11):8293-8305.
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Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling. Nat Commun. 2016 Jan 20; 7:10485.
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Aligned Electroactive TMV Nanofibers as Enabling Scaffold for Neural Tissue Engineering. Biomacromolecules. 2015 Nov 09; 16(11):3466-72.
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PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders. PLoS One. 2013; 8(12):e80737.
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In vivo and in vitro oncogenic effects of HIF2A mutations in pheochromocytomas and paragangliomas. Endocr Relat Cancer. 2013 Jun; 20(3):349-59.
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A high-throughput screen to identify inhibitors of SOD1 transcription. Front Biosci (Elite Ed). 2012 06 01; 4(8):2701-8.