"Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
| Descriptor ID |
D020738
|
| MeSH Number(s) |
D06.472.699.042.500 D12.644.276.024.500 D12.644.548.011.500 D12.776.467.024.500 D23.529.024.500
|
| Concept/Terms |
Leptin- Leptin
- Obese Protein
- Obese Gene Product
- Gene Product, Obese
- Ob Gene Product
- Gene Product, Ob
- Ob Protein
|
Below are MeSH descriptors whose meaning is more general than "Leptin".
Below are MeSH descriptors whose meaning is more specific than "Leptin".
This graph shows the total number of publications written about "Leptin" by people in this website by year, and whether "Leptin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 5 | 5 |
| 1999 | 0 | 2 | 2 |
| 2000 | 1 | 3 | 4 |
| 2001 | 2 | 1 | 3 |
| 2002 | 1 | 2 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 4 | 1 | 5 |
| 2005 | 3 | 3 | 6 |
| 2006 | 4 | 5 | 9 |
| 2007 | 1 | 4 | 5 |
| 2008 | 2 | 3 | 5 |
| 2009 | 2 | 2 | 4 |
| 2010 | 7 | 10 | 17 |
| 2011 | 4 | 4 | 8 |
| 2012 | 5 | 4 | 9 |
| 2013 | 2 | 4 | 6 |
| 2014 | 3 | 4 | 7 |
| 2015 | 4 | 5 | 9 |
| 2016 | 6 | 2 | 8 |
| 2017 | 0 | 5 | 5 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 3 | 4 |
| 2020 | 5 | 2 | 7 |
| 2021 | 1 | 2 | 3 |
| 2022 | 1 | 3 | 4 |
| 2023 | 3 | 3 | 6 |
| 2024 | 2 | 1 | 3 |
| 2025 | 3 | 1 | 4 |
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Below are the most recent publications written about "Leptin" by people in Profiles.
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Adipokines and Transitions in Metabolic Health Over Time: The Atherosclerosis Risk In Communities (ARIC) Study. J Clin Endocrinol Metab. 2025 Aug 07; 110(9):e2939-e2945.
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Leptin levels are associated with coronary artery calcification in patients with advanced prostate cancer. Oncologist. 2025 Aug 04; 30(8).
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Laparoscopically confirmed endometriosis and midlife plasma markers of inflammation, cholesterol, and adipokines among participants in the Nurses' Health Study II. Maturitas. 2025 Sep; 200:108663.
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The small GTPase Rap1 in POMC neurons regulates leptin actions and glucose metabolism. Mol Metab. 2025 May; 95:102117.
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Measurement of?energy availability in highly trained male endurance athletes and examination of its associations with bone health and endocrine function. Eur J Nutr. 2024 Oct; 63(7):2655-2665.
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Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intake. Geroscience. 2024 Oct; 46(5):4809-4826.
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Leptin deficiency, a potential mechanism for impaired fetal lung development in uteroplacental insufficiency? Pediatr Res. 2024 May; 95(6):1410-1411.
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Leptin Decreases Gluconeogenesis and Gluconeogenic Substrate Availability in Patients With Lipodystrophy. J Clin Endocrinol Metab. 2023 12 21; 109(1):e209-e215.
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Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders. Sci Transl Med. 2023 11 22; 15(723):eade8460.
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Baseline leptin predicts response to metformin in adolescents with type 1 diabetes and increased body mass index. Diabetes Obes Metab. 2023 11; 25(11):3420-3423.