"GRB7 Adaptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A SH2 DOMAIN-containing protein that mediates SIGNAL TRANSDUCTION pathways from multiple CELL SURFACE RECEPTORS, including the EPHB1 RECEPTOR. It interacts with FOCAL ADHESION KINASE and is involved in CELL MIGRATION.
| Descriptor ID |
D051382
|
| MeSH Number(s) |
D12.644.360.024.299 D12.776.157.057.043 D12.776.476.024.379
|
| Concept/Terms |
GRB7 Adaptor Protein- GRB7 Adaptor Protein
- GRB7 Protein
- Growth Factor Receptor-Bound Protein-7
- Growth Factor Receptor Bound Protein 7
|
Below are MeSH descriptors whose meaning is more general than "GRB7 Adaptor Protein".
Below are MeSH descriptors whose meaning is more specific than "GRB7 Adaptor Protein".
This graph shows the total number of publications written about "GRB7 Adaptor Protein" by people in this website by year, and whether "GRB7 Adaptor Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "GRB7 Adaptor Protein" by people in Profiles.
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An Integrative Analysis to Identify Driver Genes in Esophageal Squamous Cell Carcinoma. PLoS One. 2015; 10(10):e0139808.
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Targeting SH2 domains in breast cancer. Future Med Chem. 2014; 6(17):1909-26.
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The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer. EMBO J. 1994 Mar 15; 13(6):1331-40.