Shc Signaling Adaptor Proteins
"Shc Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of signaling adaptor proteins that contain SRC HOMOLOGY DOMAINS. Many members of this family are involved in transmitting signals from CELL SURFACE RECEPTORS to MITOGEN-ACTIVATED PROTEIN KINASES.
| Descriptor ID |
D055765
|
| MeSH Number(s) |
D12.644.360.024.330 D12.776.157.057.162 D12.776.476.024.424
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Shc Signaling Adaptor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Shc Signaling Adaptor Proteins".
This graph shows the total number of publications written about "Shc Signaling Adaptor Proteins" by people in this website by year, and whether "Shc Signaling Adaptor Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Shc Signaling Adaptor Proteins" by people in Profiles.
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Involvement of Essential Signaling Cascades and Analysis of Gene Networks in Diabesity. Genes (Basel). 2020 10 25; 11(11).
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SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E6068-77.
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Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli. Nat Struct Mol Biol. 2013 May; 20(5):620-7.
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Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice. J Clin Invest. 2010 Mar; 120(3):778-90.
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Estrogen dendrimer conjugates that preferentially activate extranuclear, nongenomic versus genomic pathways of estrogen action. Mol Endocrinol. 2006 Mar; 20(3):491-502.
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Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum. Alcohol Clin Exp Res. 1999 Oct; 23(10):1691-7.
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Activation loop tyrosines contribute varying roles to TrkB autophosphorylation and signal transduction. Oncogene. 1998 Apr 02; 16(13):1691-700.