Src Homology 2 Domain-Containing, Transforming Protein 3
"Src Homology 2 Domain-Containing, Transforming Protein 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An SHC-signaling adaptor protein that links GROWTH FACTOR RECEPTORS to SIGNAL TRANSDUCTION PATHWAYS in neurons, including NEUROTROPHINS signaling in the CENTRAL NERVOUS SYSTEM.
Descriptor ID |
D000071427
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MeSH Number(s) |
D12.644.360.024.330.875 D12.776.157.057.162.875 D12.776.476.024.424.875
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Concept/Terms |
Src Homology 2 Domain-Containing, Transforming Protein 3- Src Homology 2 Domain-Containing, Transforming Protein 3
- Src Homology 2 Domain Containing, Transforming Protein 3
- SHC3 Protein
- SHC3 (Src Homology 2 Domain-Containing) Protein
- Src Homology 2 Domain-Containing-Transforming Protein C3
- Src Homology 2 Domain Containing Transforming Protein C3
- SHCC Protein
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Below are MeSH descriptors whose meaning is more general than "Src Homology 2 Domain-Containing, Transforming Protein 3".
Below are MeSH descriptors whose meaning is more specific than "Src Homology 2 Domain-Containing, Transforming Protein 3".
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Below are the most recent publications written about "Src Homology 2 Domain-Containing, Transforming Protein 3" by people in Profiles.
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RAI(ShcC/N-Shc)-dependent recruitment of GAB 1 to RET oncoproteins potentiates PI 3-K signalling in thyroid tumors. Oncogene. 2005 Sep 15; 24(41):6303-13.
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Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135. Biochem Biophys Res Commun. 2001 Jun 22; 284(4):1039-47.
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A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain. Proc Natl Acad Sci U S A. 1996 Apr 02; 93(7):2729-34.