"GRB10 Adaptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A binding partner for several RECEPTOR PROTEIN-TYROSINE KINASES, including INSULIN RECEPTOR and INSULIN-LIKE GROWTH FACTOR RECEPTOR. It contains a C-terminal SH2 DOMAIN and mediates various SIGNAL TRANSDUCTION pathways.
Descriptor ID |
D051383
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MeSH Number(s) |
D12.644.360.024.300 D12.776.157.057.039 D12.776.476.024.380
|
Concept/Terms |
GRB10 Adaptor Protein- GRB10 Adaptor Protein
- Maternally Expressed Gene 1 Protein
- GRB10 Protein
- Growth Factor Receptor-Bound Protein 10
- Growth Factor Receptor Bound Protein 10
|
Below are MeSH descriptors whose meaning is more general than "GRB10 Adaptor Protein".
Below are MeSH descriptors whose meaning is more specific than "GRB10 Adaptor Protein".
This graph shows the total number of publications written about "GRB10 Adaptor Protein" by people in this website by year, and whether "GRB10 Adaptor Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "GRB10 Adaptor Protein" by people in Profiles.
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Hypothalamic Grb10 enhances leptin signalling and promotes weight loss. Nat Metab. 2023 01; 5(1):147-164.
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The neuropilin-like protein ESDN regulates insulin signaling and sensitivity. Am J Physiol Heart Circ Physiol. 2016 05 01; 310(9):H1184-93.
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Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors. PLoS One. 2014; 9(8):e93676.
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Comprehensive molecular characterization of clear cell renal cell carcinoma. Nature. 2013 Jul 04; 499(7456):43-9.
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Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark. Hum Mol Genet. 2003 May 01; 12(9):1005-19.
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Human GRB10 is imprinted and expressed from the paternal and maternal allele in a highly tissue- and isoform-specific fashion. Hum Mol Genet. 2000 Jul 01; 9(11):1587-95.