Homer Scaffolding Proteins

"Homer Scaffolding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome.


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This graph shows the total number of publications written about "Homer Scaffolding Proteins" by people in this website by year, and whether "Homer Scaffolding Proteins" was a major or minor topic of these publications.
Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 2004 and 2007 and 2009 and 2013
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