Death Domain Receptor Signaling Adaptor Proteins
"Death Domain Receptor Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS.
Descriptor ID |
D053418
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MeSH Number(s) |
D12.644.360.024.285 D12.644.360.075.421 D12.776.157.057.018 D12.776.476.024.320 D12.776.476.075.421
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Death Domain Receptor Signaling Adaptor Proteins".
Below are MeSH descriptors whose meaning is more specific than "Death Domain Receptor Signaling Adaptor Proteins".
This graph shows the total number of publications written about "Death Domain Receptor Signaling Adaptor Proteins" by people in this website by year, and whether "Death Domain Receptor Signaling Adaptor Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2011 | 1 | 1 | 2 |
2012 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Death Domain Receptor Signaling Adaptor Proteins" by people in Profiles.
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A Multi-center Genome-wide Association Study of Cervical Dystonia. Mov Disord. 2021 12; 36(12):2795-2801.
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NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus. J Cell Biol. 2017 06 05; 216(6):1795-1810.
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Distinct gene expression profiles in two cases of Merkel cell polyomavirus-negative Merkel cell carcinoma: shedding light on an esoteric entity. Int J Dermatol. 2015 Dec; 54(12):e549-51.
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TDP-43 affects splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways. Nucleic Acids Res. 2015 Oct 15; 43(18):8990-9005.
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Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 Jun; 7(3):374-382.
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Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice. Cell Death Differ. 2013 Sep; 20(9):1174-82.
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PIDD death-domain phosphorylation by ATM controls prodeath versus prosurvival PIDDosome signaling. Mol Cell. 2012 Sep 14; 47(5):681-93.
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Caspase-2: the orphan caspase. Cell Death Differ. 2012 Jan; 19(1):51-7.
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Cell-surface galectin-3 confers resistance to TRAIL by impeding trafficking of death receptors in metastatic colon adenocarcinoma cells. Cell Death Differ. 2012 Mar; 19(3):523-33.
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DEDD and DEDD2 associate with caspase-8/10 and signal cell death. Oncogene. 2003 Jan 16; 22(2):291-7.