TNF Receptor-Associated Death Domain Protein
"TNF Receptor-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE 1. It facilitates the recruitment of signaling proteins such as TNF RECEPTOR-ASSOCIATED FACTOR 2 and FAS ASSOCIATED DEATH DOMAIN PROTEIN to the receptor complex.
| Descriptor ID |
D053199
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| MeSH Number(s) |
D12.644.360.024.285.600 D12.644.360.024.500.249 D12.644.360.075.421.600 D12.776.157.057.018.600 D12.776.157.057.500.249 D12.776.476.024.320.775 D12.776.476.024.500.249 D12.776.476.075.421.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Death Domain Protein".
This graph shows the total number of publications written about "TNF Receptor-Associated Death Domain Protein" by people in this website by year, and whether "TNF Receptor-Associated Death Domain Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "TNF Receptor-Associated Death Domain Protein" by people in Profiles.
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The tumour suppressor Ras-association domain family protein 1A (RASSF1A) regulates TNF-a signalling in cardiomyocytes. Cardiovasc Res. 2014 Jul 01; 103(1):47-59.
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Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma. Oncogene. 2007 Mar 01; 26(10):1385-97.
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A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. Clin Cancer Res. 2006 Mar 15; 12(6):1828-38.
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Mechanism of chronic obstructive uropathy: increased expression of apoptosis-promoting molecules. Kidney Int. 2000 Oct; 58(4):1481-91.
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Sequence, genomic organization, and chromosome localization of the mouse TRADD gene. J Inflamm. 1995-1996; 46(3):168-75.