Fas-Associated Death Domain Protein
"Fas-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
| Descriptor ID |
D053200
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| MeSH Number(s) |
D12.644.360.024.285.200 D12.644.360.024.500.124 D12.644.360.075.421.200 D12.776.157.057.018.200 D12.776.157.057.500.124 D12.776.476.024.320.550 D12.776.476.024.500.124 D12.776.476.075.421.200
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| Concept/Terms |
Fas-Associated Death Domain Protein- Fas-Associated Death Domain Protein
- Fas-Associating Protein with Death Domain
- Fas Associating Protein with Death Domain
- MORT1 Protein
- Fas Associated Death Domain Protein
- FADD Protein, Fas-Associating
- FADD Protein, Fas Associating
- Fas-Associating FADD Protein
- Fas-Associating Protein FADD
- FADD, Fas-Associating Protein
- Fas Associating Protein FADD
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Below are MeSH descriptors whose meaning is more general than "Fas-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "Fas-Associated Death Domain Protein".
This graph shows the total number of publications written about "Fas-Associated Death Domain Protein" by people in this website by year, and whether "Fas-Associated Death Domain Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fas-Associated Death Domain Protein" by people in Profiles.
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Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Cell Death Dis. 2020 05 04; 11(5):305.
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Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample. Mol Neurodegener. 2017 03 20; 12(1):26.
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The peptide derived from the Ig-like domain of human herpesvirus 8 K1 protein induces death in hematological cancer cells. J Exp Clin Cancer Res. 2012 Aug 28; 31:69.
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Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas. Hum Pathol. 2011 Aug; 42(8):1117-24.
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The adaptor protein TRIP6 antagonizes Fas-induced apoptosis but promotes its effect on cell migration. Mol Cell Biol. 2010 Dec; 30(23):5582-96.
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Characterization of cytoplasmic caspase-2 activation by induced proximity. Mol Cell. 2009 Sep 24; 35(6):830-40.
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Mechanism of Fas signaling regulation by human herpesvirus 8 K1 oncoprotein. J Natl Cancer Inst. 2009 Mar 18; 101(6):399-411.
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Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL. J Neurooncol. 2009 Jul; 93(3):303-18.
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Fas-negative osteosarcoma tumor cells are selected during metastasis to the lungs: the role of the Fas pathway in the metastatic process of osteosarcoma. Mol Cancer Res. 2007 Oct; 5(10):991-9.
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Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death. Cancer. 2007 May 15; 109(10):2142-53.