TNF Receptor-Associated Factor 6
"TNF Receptor-Associated Factor 6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A signal transducing tumor necrosis factor receptor associated factor that is involved in regulation of NF-KAPPA B signalling and activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES.
| Descriptor ID |
D048029
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| MeSH Number(s) |
D12.644.360.024.500.968 D12.776.157.057.500.968 D12.776.476.024.500.968
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Factor 6".
Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Factor 6".
This graph shows the total number of publications written about "TNF Receptor-Associated Factor 6" by people in this website by year, and whether "TNF Receptor-Associated Factor 6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "TNF Receptor-Associated Factor 6" by people in Profiles.
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Bortezomib enhances radiosensitivity in oral cancer through inducing autophagy-mediated TRAF6 oncoprotein degradation. J Exp Clin Cancer Res. 2018 Apr 27; 37(1):91.
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Homozygous deletion of RAG1, RAG2 and 5' region TRAF6 causes severe immune suppression and atypical osteopetrosis. Clin Genet. 2017 Jun; 91(6):902-907.
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Integrin a3?1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt. Mol Biol Cell. 2015 May 15; 26(10):1857-74.
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STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nat Commun. 2014 Dec 15; 5:5798.
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Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling. J Virol. 2011 Jul; 85(13):6212-9.
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The large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis. PLoS One. 2011 Mar 03; 6(3):e17161.
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Signaling of interleukin-17 family cytokines in immunity and inflammation. Cell Signal. 2011 Jul; 23(7):1069-75.
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TAK1 lysine 158 is required for TGF-?-induced TRAF6-mediated Smad-independent IKK/NF-?B and JNK/AP-1 activation. Cell Signal. 2011 Jan; 23(1):222-7.
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RKIP inhibits NF-kappaB in cancer cells by regulating upstream signaling components of the IkappaB kinase complex. FEBS Lett. 2010 Feb 19; 584(4):662-8.
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Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation. J Biol Chem. 2010 Feb 19; 285(8):5347-60.