Severe Combined Immunodeficiency
"Severe Combined Immunodeficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).
| Descriptor ID |
D016511
|
| MeSH Number(s) |
C16.614.815 C18.452.284.800 C20.673.815
|
| Concept/Terms |
Severe Combined Immunodeficiency- Severe Combined Immunodeficiency
- Combined Immunodeficiencies, Severe
- Combined Immunodeficiency, Severe
- Immunodeficiencies, Severe Combined
- Severe Combined Immunodeficiencies
- Immunodeficiency, Severe Combined
- Severe Combined Immune Deficiency
- Severe Combined Immunodeficiency Syndrome
- Severe Combined Immunologic Deficiency
- Immunodeficiency Syndrome, Severe Combined
- Immunologic Deficiency, Severe Combined
Bare Lymphocyte Syndrome- Bare Lymphocyte Syndrome
- Bare Lymphocyte Syndromes
- Lymphocyte Syndrome, Bare
- Lymphocyte Syndromes, Bare
- Syndrome, Bare Lymphocyte
- Syndromes, Bare Lymphocyte
Omenn Syndrome- Omenn Syndrome
- Syndrome, Omenn
- Reticuloendotheliosis, Familial
- Familial Reticuloendothelioses
- Familial Reticuloendotheliosis
- Reticuloendothelioses, Familial
- Omenn's Syndrome
- Omenns Syndrome
- Syndrome, Omenn's
|
Below are MeSH descriptors whose meaning is more general than "Severe Combined Immunodeficiency".
Below are MeSH descriptors whose meaning is more specific than "Severe Combined Immunodeficiency".
This graph shows the total number of publications written about "Severe Combined Immunodeficiency" by people in this website by year, and whether "Severe Combined Immunodeficiency" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 |
| 1999 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 3 | 1 | 4 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 1 | 4 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 5 | 0 | 5 |
| 2018 | 4 | 0 | 4 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 2 | 0 | 2 |
| 2022 | 3 | 0 | 3 |
| 2023 | 2 | 0 | 2 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Severe Combined Immunodeficiency" by people in Profiles.
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A Unique Comprehensive Model to Screen Newborns for Severe Combined Immunodeficiency-An Ontario Single-Centre Experience Spanning 2013-2023. Genes (Basel). 2024 Jul 15; 15(7).
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Relevance of lymphocyte proliferation to PHA in severe combined immunodeficiency (SCID) and T cell lymphopenia. Clin Immunol. 2024 04; 261:109942.
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Posttransplantation late complications increase over time for patients with SCID: A?Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study. J Allergy Clin Immunol. 2024 01; 153(1):287-296.
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Measuring the effect of newborn screening on survival after haematopoietic cell transplantation for severe combined immunodeficiency: a 36-year longitudinal study from the Primary Immune Deficiency Treatment Consortium. Lancet. 2023 07 08; 402(10396):129-140.
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The diagnosis of severe combined immunodeficiency: Implementation of the PIDTC 2022 Definitions. J Allergy Clin Immunol. 2023 02; 151(2):547-555.e5.
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The diagnosis of severe combined immunodeficiency (SCID): The Primary Immune Deficiency Treatment Consortium (PIDTC) 2022 Definitions. J Allergy Clin Immunol. 2023 02; 151(2):539-546.
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Outcomes following treatment for ADA-deficient severe combined immunodeficiency: a report from the PIDTC. Blood. 2022 08 18; 140(7):685-705.
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Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients. J Clin Immunol. 2021 10; 41(7):1633-1647.
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Combined immunodeficiency due to a mutation in the ?1 subunit of the coat protein I complex. J Clin Invest. 2021 02 01; 131(3).
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Infections in Infants with SCID: Isolation, Infection Screening, and Prophylaxis in PIDTC Centers. J Clin Immunol. 2021 01; 41(1):38-50.