bcl-Associated Death Protein
"bcl-Associated Death Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pro-apoptotic protein and member of the Bcl-2 protein family that is regulated by PHOSPHORYLATION. Unphosphorylated Bad protein inhibits the activity of BCL-XL PROTEIN.
| Descriptor ID |
D051025
|
| MeSH Number(s) |
D12.644.360.075.718.100 D12.776.476.075.718.100 D12.776.744.049
|
| Concept/Terms |
bcl-Associated Death Protein- bcl-Associated Death Protein
- Death Protein, bcl-Associated
- bcl Associated Death Protein
- bcl2-Antagonist of Cell Death Protein
- bcl2 Antagonist of Cell Death Protein
- Bad Protein
|
Below are MeSH descriptors whose meaning is more general than "bcl-Associated Death Protein".
Below are MeSH descriptors whose meaning is more specific than "bcl-Associated Death Protein".
This graph shows the total number of publications written about "bcl-Associated Death Protein" by people in this website by year, and whether "bcl-Associated Death Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "bcl-Associated Death Protein" by people in Profiles.
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Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine. Cancer Biol Ther. 2013 Jun; 14(6):492-501.
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Sox4 is required for the survival of pro-B cells. J Immunol. 2013 Mar 01; 190(5):2080-9.
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Unphosphorylated STAT1 promotes sarcoma development through repressing expression of Fas and bad and conferring apoptotic resistance. Cancer Res. 2012 Sep 15; 72(18):4724-32.
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Activation of protein kinase C delta following cerebral ischemia leads to release of cytochrome C from the mitochondria via bad pathway. PLoS One. 2011; 6(7):e22057.
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Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res. 2005 Jan 15; 65(2):613-21.
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Anti-HLA class I antibody-mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells. Hum Immunol. 2004 Apr; 65(4):291-302.
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Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias. Leukemia. 2004 Feb; 18(2):267-75.
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Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis. Circ Res. 2004 Feb 20; 94(3):362-9.
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Monogene and polygene therapy for the treatment of experimental prostate cancers by use of apoptotic genes bax and bad driven by the prostate-specific promoter ARR(2)PB. Hum Gene Ther. 2002 Nov 20; 13(17):2051-64.
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Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells. Cancer Res. 2001 Feb 15; 61(4):1699-706.