bcl-2-Associated X Protein
"bcl-2-Associated X Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.
| Descriptor ID |
D051028
|
| MeSH Number(s) |
D12.644.360.075.718.400 D12.776.476.075.718.400
|
| Concept/Terms |
bcl-2-Associated X Protein- bcl-2-Associated X Protein
- Protein, bcl-2-Associated X
- X Protein, bcl-2-Associated
- bcl 2 Associated X Protein
- Bax Apoptosis Regulator Protein
- Bax Protein
- bcl2-Associated X Protein
- bcl2 Associated X Protein
|
Below are MeSH descriptors whose meaning is more general than "bcl-2-Associated X Protein".
Below are MeSH descriptors whose meaning is more specific than "bcl-2-Associated X Protein".
This graph shows the total number of publications written about "bcl-2-Associated X Protein" by people in this website by year, and whether "bcl-2-Associated X Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 8 | 8 |
| 1997 | 0 | 11 | 11 |
| 1998 | 0 | 14 | 14 |
| 1999 | 0 | 10 | 10 |
| 2000 | 0 | 19 | 19 |
| 2001 | 0 | 20 | 20 |
| 2002 | 0 | 22 | 22 |
| 2003 | 0 | 16 | 16 |
| 2004 | 0 | 12 | 12 |
| 2005 | 2 | 13 | 15 |
| 2006 | 1 | 9 | 10 |
| 2007 | 2 | 6 | 8 |
| 2008 | 2 | 6 | 8 |
| 2009 | 3 | 8 | 11 |
| 2010 | 3 | 10 | 13 |
| 2011 | 0 | 9 | 9 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 3 | 4 |
| 2014 | 1 | 3 | 4 |
| 2015 | 1 | 6 | 7 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "bcl-2-Associated X Protein" by people in Profiles.
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Immunological mechanisms of the nucleocapsid protein in COVID-19. Sci Rep. 2024 02 14; 14(1):3711.
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BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction. J Mol Cell Cardiol. 2023 11; 184:1-12.
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Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics. Blood Cancer J. 2023 04 24; 13(1):57.
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Maximal Activation of Apoptosis Signaling by Cotargeting Antiapoptotic Proteins in BH3 Mimetic-Resistant AML and AML Stem Cells. Mol Cancer Ther. 2022 06 01; 21(6):879-889.
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Therapeutic Synergy in Esophageal Cancer and Mesothelioma Is Predicted by Dynamic BH3 Profiling. Mol Cancer Ther. 2021 08; 20(8):1469-1480.
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The role of FAS, FAS-L, BAX, and BCL-2 gene polymorphisms in determining susceptibility to unexplained recurrent pregnancy loss. J Assist Reprod Genet. 2019 May; 36(5):995-1002.
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Cellular uptake and apoptotic potential of rhenium labeled magnetic protein cages in MDA-MB-231 cells. Environ Toxicol Pharmacol. 2018 Oct; 63:127-134.
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Ablation of Bax and Bak protects skeletal muscle against pressure-induced injury. Sci Rep. 2018 02 27; 8(1):3689.
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Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak. Elife. 2017 11 17; 6.
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Muscadine Grape Skin Extract Induces an Unfolded Protein Response-Mediated Autophagy in Prostate Cancer Cells: A TMT-Based Quantitative Proteomic Analysis. PLoS One. 2016; 11(10):e0164115.