Hypoxia-Inducible Factor 1
"Hypoxia-Inducible Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that plays a role in APOPTOSIS. It is composed of two subunits: ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR and HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT.
| Descriptor ID |
D051793
|
| MeSH Number(s) |
D12.776.260.103.625 D12.776.930.125.625
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1" by people in this website by year, and whether "Hypoxia-Inducible Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 6 | 6 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 4 | 4 |
| 2005 | 2 | 3 | 5 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 5 | 3 | 8 |
| 2009 | 2 | 1 | 3 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 2 | 3 |
| 2014 | 0 | 1 | 1 |
| 2017 | 2 | 1 | 3 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1" by people in Profiles.
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Hypoxia-Inducible Factor 1 Alpha Is Dispensable for Host Defense of Group B Streptococcus Colonization and Infection. J Innate Immun. 2021; 13(6):391-403.
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Resolving the HIF paradox in pancreatic cancer. Cancer Lett. 2020 10 01; 489:50-55.
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Hypoxia inducible factor (HIF) in the tumor microenvironment: friend or foe? Sci China Life Sci. 2017 Oct; 60(10):1114-1124.
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Hypoxia and Bone Metastatic Disease. Curr Osteoporos Rep. 2017 08; 15(4):231-238.
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Modeling the Genetic Regulation of Cancer Metabolism: Interplay between Glycolysis and Oxidative Phosphorylation. Cancer Res. 2017 04 01; 77(7):1564-1574.
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Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells. Curr Biol. 2017 Feb 06; 27(3):392-400.
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The ever-expanding role of HIF in tumour and stromal biology. Nat Cell Biol. 2016 Apr; 18(4):356-65.
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Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin. Genes Dev. 2015 Apr 15; 29(8):817-31.
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HIF targets in bone remodeling and metastatic disease. Pharmacol Ther. 2015 Jun; 150:169-77.
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The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation. J Clin Invest. 2014 Jun; 124(6):2640-50.