Hypoxia-Inducible Factor 1, alpha Subunit
"Hypoxia-Inducible Factor 1, alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN.
| Descriptor ID |
D051795
|
| MeSH Number(s) |
D12.776.260.103.625.750 D12.776.930.125.625.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1, alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1, alpha Subunit".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in this website by year, and whether "Hypoxia-Inducible Factor 1, alpha Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 1 | 3 |
| 2013 | 2 | 3 | 5 |
| 2014 | 1 | 5 | 6 |
| 2015 | 3 | 4 | 7 |
| 2016 | 3 | 1 | 4 |
| 2017 | 3 | 5 | 8 |
| 2018 | 3 | 1 | 4 |
| 2019 | 3 | 3 | 6 |
| 2020 | 3 | 2 | 5 |
| 2021 | 2 | 1 | 3 |
| 2025 | 2 | 3 | 5 |
| 2026 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in Profiles.
-
Combined Therapy Versus Fortified Anti-VEGF Monotherapy in Type C Polypoidal Choroidal Vasculopathy: Long-Term Outcomes and Exploratory Biomarker Insights. Int J Mol Sci. 2026 Jan 26; 27(3).
-
A non-canonical role for HIF-1a: redirecting DGCR8 to the RNA exosome for snoRNA degradation and translational modulation. Nucleic Acids Res. 2026 Jan 22; 54(3).
-
Signal Transducer and Activator of Transcription (STAT) Proteins Regulate Mucosal-Associated Invariant T (MAIT) Cell Function. Immunology. 2026 05; 178(1):97-108.
-
Retinal Ischemia: Therapeutic Effects and Mechanisms of Paeoniflorin. Int J Mol Sci. 2025 Nov 11; 26(22).
-
Acrolein-induced PKM2 modification drives NETosis and glioma progression. Free Radic Biol Med. 2025 Dec 16; 241:567-581.
-
Restricting metabolic plasticity enhances stress adaptation through the modulation of PDH and HIF1A in TRAP1-depleted colon cancer. Cancer Lett. 2025 Nov 01; 632:217977.
-
Sustained ROS scavenging and pericellular oxygenation by lignin composites rescue HIF-1a and VEGF levels to improve diabetic wound neovascularization and healing. Acta Biomater. 2025 08; 202:205-215.
-
Vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 alpha (HIF-1?) in lacrimal gland Adenoid cystic carcinoma: Correlation with clinical outcome. Ann Diagn Pathol. 2022 Feb; 56:151846.
-
Hypoxia-inducible factor 1-alpha enhances the secretome to rejuvenate adult cardiosphere-derived cells. J Thorac Cardiovasc Surg. 2023 02; 165(2):e56-e65.
-
Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells. J Clin Invest. 2021 04 01; 131(7).