Hypoxia-Inducible Factor 1, alpha Subunit
"Hypoxia-Inducible Factor 1, alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hypoxia-inducible factor 1, alpha subunit is a basic helix-loop-helix transcription factor that is regulated by OXYGEN availability and is targeted for degradation by VHL TUMOR SUPPRESSOR PROTEIN.
| Descriptor ID |
D051795
|
| MeSH Number(s) |
D12.776.260.103.625.750 D12.776.930.125.625.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hypoxia-Inducible Factor 1, alpha Subunit".
Below are MeSH descriptors whose meaning is more specific than "Hypoxia-Inducible Factor 1, alpha Subunit".
This graph shows the total number of publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in this website by year, and whether "Hypoxia-Inducible Factor 1, alpha Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 6 | 6 |
| 2002 | 0 | 8 | 8 |
| 2003 | 0 | 6 | 6 |
| 2004 | 0 | 13 | 13 |
| 2005 | 0 | 10 | 10 |
| 2006 | 2 | 2 | 4 |
| 2007 | 7 | 5 | 12 |
| 2008 | 4 | 7 | 11 |
| 2009 | 7 | 7 | 14 |
| 2010 | 11 | 3 | 14 |
| 2011 | 6 | 11 | 17 |
| 2012 | 9 | 6 | 15 |
| 2013 | 4 | 6 | 10 |
| 2014 | 9 | 7 | 16 |
| 2015 | 6 | 7 | 13 |
| 2016 | 6 | 5 | 11 |
| 2017 | 11 | 7 | 18 |
| 2018 | 7 | 10 | 17 |
| 2019 | 5 | 5 | 10 |
| 2020 | 4 | 4 | 8 |
| 2021 | 3 | 1 | 4 |
| 2023 | 0 | 2 | 2 |
| 2024 | 5 | 1 | 6 |
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Below are the most recent publications written about "Hypoxia-Inducible Factor 1, alpha Subunit" by people in Profiles.
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HIF1a-regulated glycolysis promotes activation-induced cell death and IFN-? induction in hypoxic T cells. Nat Commun. 2024 Oct 30; 15(1):9394.
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Role of HIF-1a-Activated IL-22/IL-22R1/Bmi1 Signaling Modulates the Self-Renewal of Cardiac Stem Cells in Acute Myocardial Ischemia. Stem Cell Rev Rep. 2024 Nov; 20(8):2194-2214.
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Mechanism and rational combinations with GP-2250, a novel oxathiazine derivative, in ovarian cancer. Cancer Med. 2024 Aug; 13(15):e70031.
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REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma. Sci Rep. 2024 06 12; 14(1):13596.
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Role of hypoxia-mediated pyroptosis?in the development of extending knee joint contracture in rats. Eur J Med Res. 2024 May 27; 29(1):298.
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HIF-1a participates in the regulation of S100A16-HRD1-GSK3?/CK1a pathway in renal hypoxia injury. Cell Death Dis. 2024 May 06; 15(5):316.
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Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2023 12 15; 29(24):5183-5195.
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Radiation-induced bone loss in mice is ameliorated by inhibition of HIF-2a in skeletal progenitor cells. Sci Transl Med. 2023 11 29; 15(724):eabo5217.
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ABL kinases regulate the stabilization of HIF-1a and MYC through?CPSF1. Proc Natl Acad Sci U S A. 2023 04 18; 120(16):e2210418120.
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Vascular endothelial growth factor (VEGF) and hypoxia inducible factor-1 alpha (HIF-1?) in lacrimal gland Adenoid cystic carcinoma: Correlation with clinical outcome. Ann Diagn Pathol. 2022 Feb; 56:151846.