Autophagy-Related Protein 7
"Autophagy-Related Protein 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
| Descriptor ID |
D000071193
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| MeSH Number(s) |
D12.776.094.399
|
| Concept/Terms |
Autophagy-Related Protein 7- Autophagy-Related Protein 7
- Autophagy Related Protein 7
- ATG7 Protein
- Ubiquitin-Activating Enzyme E1-like Protein
- Ubiquitin Activating Enzyme E1 like Protein
- Ubiquitin-Like Modifier-Activating Enzyme ATG7
- Ubiquitin Like Modifier Activating Enzyme ATG7
- ATG12-Activating Enzyme E1 ATG7
- ATG12 Activating Enzyme E1 ATG7
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 7".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 7".
This graph shows the total number of publications written about "Autophagy-Related Protein 7" by people in this website by year, and whether "Autophagy-Related Protein 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 4 | 4 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 3 | 3 |
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Below are the most recent publications written about "Autophagy-Related Protein 7" by people in Profiles.
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Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading. Proc Natl Acad Sci U S A. 2021 07 06; 118(27).
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Autophagy inhibition rescues structural and functional defects caused by the loss of mitochondrial chaperone Hsc70-5 in Drosophila. Autophagy. 2021 10; 17(10):3160-3174.
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Potential neuron-autonomous Purkinje cell degeneration by 2',3'-cyclic nucleotide 3'-phosphodiesterase promoter/Cre-mediated autophagy impairments. FASEB J. 2021 01; 35(1):e21225.
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Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons. Elife. 2020 02 11; 9.
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A facile forward-genetic screen for Arabidopsis autophagy mutants reveals twenty-one loss-of-function mutations disrupting six ATG genes. Autophagy. 2019 06; 15(6):941-959.
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A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence. Autophagy. 2019 03; 15(3):527-542.
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The constitutive lipid droplet protein PLIN2 regulates autophagy in liver. Autophagy. 2017 Jul 03; 13(7):1130-1144.
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Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia. Blood. 2016 09 01; 128(9):1260-9.
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Autophagy machinery impaired interferon signalling pathways to benefit hepatitis B virus replication. Asian Pac J Allergy Immunol. 2016 Mar; 34(1):77-85.
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A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress. PLoS One. 2015; 10(4):e0122628.