Autophagy-Related Protein 12
"Autophagy-Related Protein 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes.
| Descriptor ID |
D000071192
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| MeSH Number(s) |
D12.776.094.391 D12.776.947.125
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| Concept/Terms |
Autophagy-Related Protein 12- Autophagy-Related Protein 12
- Autophagy Related Protein 12
- ATG12 Protein
- Ubiquitin-Like Protein ATG12
- ATG12, Ubiquitin-Like Protein
- Ubiquitin Like Protein ATG12
|
Below are MeSH descriptors whose meaning is more general than "Autophagy-Related Protein 12".
Below are MeSH descriptors whose meaning is more specific than "Autophagy-Related Protein 12".
This graph shows the total number of publications written about "Autophagy-Related Protein 12" by people in this website by year, and whether "Autophagy-Related Protein 12" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Autophagy-Related Protein 12" by people in Profiles.
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Increased ATG5-ATG12 in hepatitis B virus-associated hepatocellular carcinoma and their role in apoptosis. World J Gastroenterol. 2016 Oct 07; 22(37):8361-8374.
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Autophagy machinery impaired interferon signalling pathways to benefit hepatitis B virus replication. Asian Pac J Allergy Immunol. 2016 Mar; 34(1):77-85.
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DIRAS3 regulates the autophagosome initiation complex in dormant ovarian cancer cells. Autophagy. 2014 Jun; 10(6):1071-92.
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Dasatinib induces autophagic cell death in human ovarian cancer. Cancer. 2010 Nov 01; 116(21):4980-90.
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Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway. J Cell Biol. 2004 Sep 27; 166(7):1041-54.