Phosphoribosyl Pyrophosphate
"Phosphoribosyl Pyrophosphate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
| Descriptor ID |
D010754
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| MeSH Number(s) |
D09.894.643.650
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphoribosyl Pyrophosphate".
Below are MeSH descriptors whose meaning is more specific than "Phosphoribosyl Pyrophosphate".
This graph shows the total number of publications written about "Phosphoribosyl Pyrophosphate" by people in this website by year, and whether "Phosphoribosyl Pyrophosphate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphoribosyl Pyrophosphate" by people in Profiles.
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Pretreatment of colon carcinoma cells with Tomudex enhances 5-fluorouracil cytotoxicity. Clin Cancer Res. 1998 Feb; 4(2):469-73.
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Inhibition of phosphoribosylpyrophosphate synthetase by 4-methoxy-(MRPP) and 4-amino-8-(D-ribofuranosylamino) pyrimido[5,4-d]pyrimidine (ARPP). Biochem Pharmacol. 1989 Oct 15; 38(20):3543-9.
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Biochemical parameters of mercaptopurine activity in patients with acute lymphoblastic leukemia. Cancer Res. 1986 Mar; 46(3):1495-8.
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Cellular pharmacokinetics of mercaptopurine in human neoplastic cells and cell lines. Cancer Res. 1985 Sep; 45(9):4156-61.
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Synergistic interaction between acivicin (AT-125) and 6-thioguanine in the murine leukemia L1210. Biochemical and cytokinetic considerations. Biochem Pharmacol. 1984 Jan 15; 33(2):247-54.
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Biochemical basis for the cytotoxicity of 9-beta-D-xylofuranosyladenine in Chinese hamster ovary cells. Cancer Res. 1981 Mar; 41(3):1039-44.
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UMP pyrophosphorylase of Tetrahymena pyriformis. Partial purification and properties. Arch Biochem Biophys. 1978 Apr 15; 187(1):264-71.