p300-CBP Transcription Factors
"p300-CBP Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.
| Descriptor ID |
D050880
|
| MeSH Number(s) |
D08.811.913.050.134.415.500.575 D12.776.930.680
|
| Concept/Terms |
p300-CBP Transcription Factors- p300-CBP Transcription Factors
- Transcription Factors, p300-CBP
- p300 CBP Transcription Factors
- p300-CBP Coactivator
- Coactivator, p300-CBP
- p300 CBP Coactivator
- p300-CBP Protein
- p300 CBP Protein
|
Below are MeSH descriptors whose meaning is more general than "p300-CBP Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "p300-CBP Transcription Factors".
This graph shows the total number of publications written about "p300-CBP Transcription Factors" by people in this website by year, and whether "p300-CBP Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 3 | 3 |
| 2006 | 2 | 0 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 3 | 4 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "p300-CBP Transcription Factors" by people in Profiles.
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?-catenin functions as a molecular adapter for disordered cBAF interactions. Mol Cell. 2025 Aug 21; 85(16):3041-3056.e9.
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Supercharging BRD4 with NUT in carcinoma. Oncogene. 2021 02; 40(8):1396-1408.
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Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP. J Med Chem. 2020 05 14; 63(9):4716-4731.
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Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines. Aging Cell. 2020 04; 19(4):e13129.
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Histone Acetyltransferase p300 Induces De Novo Super-Enhancers to Drive Cellular Senescence. Mol Cell. 2019 02 21; 73(4):684-698.e8.
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Acetylation Disfavors Tau Phase Separation. Int J Mol Sci. 2018 May 04; 19(5).
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Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells. PLoS One. 2016; 11(3):e0150450.
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Genome-Wide Association Study of Staphylococcus aureus Carriage in a Community-Based Sample of Mexican-Americans in Starr County, Texas. PLoS One. 2015; 10(11):e0142130.
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Bnip3 Binds and Activates p300: Possible Role in Cardiac Transcription and Myocyte Morphology. PLoS One. 2015; 10(8):e0136847.
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lncRNA directs cooperative epigenetic regulation downstream of chemokine signals. Cell. 2014 Nov 20; 159(5):1110-1125.