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KYLE EAGEN

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Cell & Gene Therapy
    DivisionCenter for Cell & Gene Therapy

    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Precision Environmental Health
    DivisionCenter for Precision Env Health


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lemieux ME, Huang Y, Durall RT, Luong NM, Hertzler HJ, Huang J, Gokhale PC, Leeper BA, Persky NS, Root DE, Anekal PV, Montero Llopis PDLM, David CN, Kutok JL, Raimondi A, Saluja K, Luo J, Zahnow CA, Adane B, Stegmaier K, Hawkins CE, Ponne C, Le Q, Shapiro GI, Eagen KP, French CA. EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes. Cancer Res. 2023 12 01; 83(23):3956-3973. PMID: 37747726; PMCID: PMC10843040.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    2. Durall RT, Huang J, Wojenski L, Huang Y, Gokhale PC, Leeper BA, Nash JO, Ballester PL, Davidson S, Shlien A, Sotirakis E, Bertaux F, Dubus V, Luo J, Wu CJ, Keskin DB, Eagen KP, Shapiro GI, French CA. The BRD4-NUT Fusion Alone Drives Malignant Transformation of NUT Carcinoma. Cancer Res. 2023 12 01; 83(23):3846-3860. PMID: 37819236; PMCID: PMC10690098.
      Citations: 1     Fields:    Translation:HumansAnimals
    3. Huang Y, Durall RT, Luong NM, Hertzler HJ, Huang J, Gokhale PC, Leeper BA, Persky NS, Root DE, Anekal PV, Montero Llopis PDLM, David CN, Kutok JL, Raimondi A, Saluja K, Luo J, Zahnow CA, Adane B, Stegmaier K, Hawkins CE, Ponne C, Le Q, Shapiro GI, Lemieux ME, Eagen KP, French CA. EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes. bioRxiv. 2023 Aug 16. PMID: 37645799; PMCID: PMC10461970.
      Citations: 1     
    4. Eagen KP. BET proteins loop and compartmentalize the 3D genome. Nat Genet. 2022 04; 54(4):370-371. PMID: 35410382.
      Citations:    Fields:    
    5. Hogan AK, Sathyan KM, Willis AB, Khurana S, Srivastava S, Zasadzinska E, Lee AS, Bailey AO, Gaynes MN, Huang J, Bodner J, Rosencrance CD, Wong KA, Morgan MA, Eagen KP, Shilatifard A, Foltz DR. UBR7 acts as a histone chaperone for post-nucleosomal histone H3. EMBO J. 2021 12 15; 40(24):e108307. PMID: 34786730; PMCID: PMC8672181.
      Citations: 1     Fields:    Translation:HumansCells
    6. Eagen KP, French CA. Supercharging BRD4 with NUT in carcinoma. Oncogene. 2021 02; 40(8):1396-1408. PMID: 33452461; PMCID: PMC7914217.
      Citations: 11     Fields:    Translation:HumansCells
    7. Fang C, Wang Z, Han C, Safgren SL, Helmin KA, Adelman ER, Serafin V, Basso G, Eagen KP, Gaspar-Maia A, Figueroa ME, Singer BD, Ratan A, Ntziachristos P, Zang C. Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. Genome Biol. 2020 09 15; 21(1):247. PMID: 32933554; PMCID: PMC7493976.
      Citations: 18     Fields:    Translation:HumansCells
    8. Rosencrance CD, Ammouri HN, Yu Q, Ge T, Rendleman EJ, Marshall SA, Eagen KP. Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment. Mol Cell. 2020 04 02; 78(1):112-126.e12. PMID: 32243828; PMCID: PMC7164681.
      Citations: 19     Fields:    Translation:HumansCells
    9. Ge T, Rosencrance CD, Eagen KP. Contact Mapping to Unravel Chromosome Folding. Trends Biochem Sci. 2019 12; 44(12):1089-1090. PMID: 31677956; PMCID: PMC7105279.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    10. Eagen KP. Principles of Chromosome Architecture Revealed by Hi-C. Trends Biochem Sci. 2018 06; 43(6):469-478. PMID: 29685368; PMCID: PMC6028237.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    11. Eagen KP, Aiden EL, Kornberg RD. Polycomb-mediated chromatin loops revealed by a subkilobase-resolution chromatin interaction map. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):8764-8769. PMID: 28765367; PMCID: PMC5565414.
      Citations: 70     Fields:    Translation:AnimalsCells
    12. Nagai S, Davis RE, Mattei PJ, Eagen KP, Kornberg RD. Chromatin potentiates transcription. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):1536-1541. PMID: 28137832; PMCID: PMC5320956.
      Citations: 14     Fields:    Translation:AnimalsCells
    13. Eagen KP, Hartl TA, Kornberg RD. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture. Cell. 2015 Nov 05; 163(4):934-46. PMID: 26544940; PMCID: PMC4639323.
      Citations: 72     Fields:    Translation:AnimalsCells
    14. Lewis RW, Mabry J, Polisar JG, Eagen KP, Ganem B, Hess GP. Dihydropyrimidinone positive modulation of delta-subunit-containing gamma-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant. Biochemistry. 2010 Jun 15; 49(23):4841-51. PMID: 20450160; PMCID: PMC5026497.
      Citations: 9     Fields:    Translation:HumansCells
    15. Kelch BA, Eagen KP, Erciyas FP, Humphris EL, Thomason AR, Mitsuiki S, Agard DA. Structural and mechanistic exploration of acid resistance: kinetic stability facilitates evolution of extremophilic behavior. J Mol Biol. 2007 May 04; 368(3):870-83. PMID: 17382344.
      Citations: 11     Fields:    Translation:Cells
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