Histone Acetyltransferases
"Histone Acetyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze acyl group transfer from ACETYL-CoA to HISTONES forming CoA and acetyl-histones.
| Descriptor ID |
D051548
|
| MeSH Number(s) |
D08.811.913.050.134.415.500
|
| Concept/Terms |
Histone Acetyltransferases- Histone Acetyltransferases
- Acetyltransferases, Histone
- Histone Acetylase
- Acetylase, Histone
- Histone Acetyltransferase
- Acetyltransferase, Histone
|
Below are MeSH descriptors whose meaning is more general than "Histone Acetyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Histone Acetyltransferases".
This graph shows the total number of publications written about "Histone Acetyltransferases" by people in this website by year, and whether "Histone Acetyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 6 | 6 |
| 1997 | 0 | 5 | 5 |
| 1998 | 0 | 10 | 10 |
| 1999 | 0 | 9 | 9 |
| 2000 | 0 | 8 | 8 |
| 2001 | 0 | 7 | 7 |
| 2002 | 0 | 14 | 14 |
| 2003 | 0 | 15 | 15 |
| 2004 | 0 | 12 | 12 |
| 2005 | 1 | 22 | 23 |
| 2006 | 10 | 9 | 19 |
| 2007 | 8 | 7 | 15 |
| 2008 | 12 | 2 | 14 |
| 2009 | 7 | 3 | 10 |
| 2010 | 1 | 5 | 6 |
| 2011 | 4 | 2 | 6 |
| 2012 | 3 | 0 | 3 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 4 | 6 |
| 2015 | 5 | 2 | 7 |
| 2016 | 2 | 2 | 4 |
| 2017 | 5 | 1 | 6 |
| 2018 | 3 | 1 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 5 | 4 | 9 |
| 2021 | 4 | 0 | 4 |
| 2022 | 0 | 1 | 1 |
| 2024 | 3 | 2 | 5 |
To return to the timeline,
click here.
Below are the most recent publications written about "Histone Acetyltransferases" by people in Profiles.
-
KAT tales: Functions of Gcn5 and PCAF lysine acetyltransferases in SAGA and ATAC. J Biol Chem. 2024 Oct; 300(10):107744.
-
KAT2A and KAT2B prevent double-stranded RNA accumulation and interferon signaling to maintain intestinal stem cell renewal. Sci Adv. 2024 Aug 09; 10(32):eadl1584.
-
Inhibition of lysine acetyltransferase KAT6 in ER+HER2- metastatic breast cancer: a phase 1 trial. Nat Med. 2024 Aug; 30(8):2242-2250.
-
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma. Sci Adv. 2024 May 31; 10(22):eadm9449.
-
High Clinical Exome Sequencing Diagnostic Rates and Novel Phenotypic Expansions for Nonisolated Microphthalmia, Anophthalmia, and Coloboma. Invest Ophthalmol Vis Sci. 2024 Mar 05; 65(3):25.
-
A novel ubiquitin-proteasome system regulation of Sgf73/ataxin-7 that maintains the integrity of the coactivator SAGA in orchestrating transcription. Genetics. 2023 07 06; 224(3).
-
A Saccharomyces cerevisiae model and screen to define the functional consequences of oncogenic histone missense mutations. G3 (Bethesda). 2022 07 06; 12(7).
-
Structure-activity relationship and antitumor activity of 1,4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP. Eur J Med Chem. 2022 Jul 05; 237:114407.
-
Epilepsy in KAT6A syndrome: Description of two individuals and revision of the literature. Eur J Med Genet. 2022 Jan; 65(1):104380.
-
Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function. Nat Commun. 2021 11 03; 12(1):6340.