"Twist-Related Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that was originally identified in DROSOPHILA as essential for proper gastrulation and MESODERM formation. It plays an important role in EMBRYONIC DEVELOPMENT and CELL DIFFERENTIATION of MUSCLE CELLS, and is found in a wide variety of organisms.
| Descriptor ID |
D051879
|
| MeSH Number(s) |
D12.776.260.103.906.250 D12.776.930.125.906.250
|
| Concept/Terms |
Twist-Related Protein 1- Twist-Related Protein 1
- Twist Related Protein 1
- Twist Transcription Factor
- Transcription Factor, Twist
- Twist Protein
- TWIST1 Protein
- Twist Family Bhlh Transcription Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Twist-Related Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Twist-Related Protein 1".
This graph shows the total number of publications written about "Twist-Related Protein 1" by people in this website by year, and whether "Twist-Related Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Twist-Related Protein 1" by people in Profiles.
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Molecular mechanisms of TWIST1-regulated transcription in EMT and cancer metastasis. EMBO Rep. 2023 11 06; 24(11):e56902.
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ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat. Eur J Cell Biol. 2023 Sep; 102(3):151341.
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Vertical transmission of a large calvarial ossification defect due to heterozygous variants of ALX4 and TWIST1. Am J Med Genet A. 2021 03; 185(3):916-922.
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PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019 03 01; 129(3):1129-1151.
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DPYSL3 modulates mitosis, migration, and epithelial-to-mesenchymal transition in claudin-low breast cancer. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E11978-E11987.
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Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma. Nat Genet. 2018 04; 50(4):515-523.
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Breast tumor cell-specific knockout of Twist1 inhibits cancer cell plasticity, dissemination, and lung metastasis in mice. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):11494-11499.
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Intercellular Genetic Interaction Between Irf6 and Twist1 during Craniofacial Development. Sci Rep. 2017 08 02; 7(1):7129.
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DNMT3A mutation leads to leukemic extramedullary infiltration mediated by TWIST1. J Hematol Oncol. 2016 10 10; 9(1):106.
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Twist1 promotes breast cancer invasion and metastasis by silencing Foxa1 expression. Oncogene. 2017 02 23; 36(8):1157-1166.