"POU Domain Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.
| Descriptor ID |
D050809
|
| MeSH Number(s) |
D12.776.260.655 D12.776.930.710
|
| Concept/Terms |
POU Domain Factors- POU Domain Factors
- Pit-Oct-Unc Proteins
- Pit Oct Unc Proteins
- POU Proteins
- Transcription Factor POU
- POU, Transcription Factor
|
Below are MeSH descriptors whose meaning is more general than "POU Domain Factors".
Below are MeSH descriptors whose meaning is more specific than "POU Domain Factors".
This graph shows the total number of publications written about "POU Domain Factors" by people in this website by year, and whether "POU Domain Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "POU Domain Factors" by people in Profiles.
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POU3F3-related disorder: Defining the phenotype and expanding the molecular spectrum. Clin Genet. 2023 08; 104(2):186-197.
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Single-Cell Transcriptomes Reveal Diverse Regulatory Strategies for Olfactory Receptor Expression and Axon Targeting. Curr Biol. 2020 04 06; 30(7):1189-1198.e5.
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The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Sci Transl Med. 2018 12 19; 10(472).
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A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITFhigh /AXLlow melanoma. Pigment Cell Melanoma Res. 2019 03; 32(2):280-291.
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Fluorescent fusion protein knockout mediated by anti-GFP nanobody. Nat Struct Mol Biol. 2011 Dec 11; 19(1):117-21.
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The forkhead transcription factor FoxB1 regulates the dorsal-ventral and anterior-posterior patterning of the ectoderm during early Xenopus embryogenesis. Dev Biol. 2011 Dec 01; 360(1):11-29.
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Abnormal polarization and axon outgrowth in retinal ganglion cells lacking the POU-domain transcription factor Brn-3b. Mol Cell Neurosci. 2000 Aug; 16(2):141-56.
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Distinct steady-state nuclear receptor coregulator complexes exist in vivo. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11697-702.
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A novel class of murine POU gene predominantly expressed in central nervous system. J Biol Chem. 1993 Apr 05; 268(10):7449-57.
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Cloning, chromosomal localization and expression pattern of the POU domain gene Oct-11. Nucleic Acids Res. 1993 Jan 11; 21(1):127-34.