Transcription Factor Brn-3
"Transcription Factor Brn-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of mammalian POU domain factors that are expressed predominately in NEURONS.
| Descriptor ID |
D050818
|
| MeSH Number(s) |
D12.776.260.655.625 D12.776.930.710.625
|
| Concept/Terms |
Transcription Factor Brn-3- Transcription Factor Brn-3
- Brn-3, Transcription Factor
- Transcription Factor Brn 3
- Brn-3 Transcription Factor
- Brn 3 Transcription Factor
- Transcription Factor, Brn-3
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor Brn-3".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor Brn-3".
This graph shows the total number of publications written about "Transcription Factor Brn-3" by people in this website by year, and whether "Transcription Factor Brn-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor Brn-3" by people in Profiles.
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Identification of an N-terminal transcriptional activation domain within Brn3b/POU4f2. Differentiation. 2005 Feb; 73(1):18-27.
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The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells. Neurosci Lett. 2002 Dec 06; 334(1):1-4.
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Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan; 129(2):467-77.
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Requirement for math5 in the development of retinal ganglion cells. Genes Dev. 2001 Jan 01; 15(1):24-9.
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Abnormal polarization and axon outgrowth in retinal ganglion cells lacking the POU-domain transcription factor Brn-3b. Mol Cell Neurosci. 2000 Aug; 16(2):141-56.
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POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification. Dev Biol. 1999 Jun 15; 210(2):469-80.
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Development of the mouse inner ear and origin of its sensory organs. J Neurosci. 1998 May 01; 18(9):3327-35.
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Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9445-50.
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Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems. Cold Spring Harb Symp Quant Biol. 1997; 62:325-36.