Transcription Factor Brn-3C
"Transcription Factor Brn-3C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A POU domain factor that activates neuronal cell GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS, alpha internexin, and SYNAPTOSOMAL-ASSOCIATED PROTEIN 25. Mutations in the Brn-3c gene have been associated with DEAFNESS.
Descriptor ID |
D050821
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MeSH Number(s) |
D12.776.260.655.625.500 D12.776.930.710.625.875
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Concept/Terms |
Transcription Factor Brn-3C- Transcription Factor Brn-3C
- Brn-3C, Transcription Factor
- Transcription Factor Brn 3C
- Brn-3c Transcription Factor
- Brn 3c Transcription Factor
- Transcription Factor, Brn-3c
- Pou4f3 Transcription Factor
- Transcription Factor, Pou4f3
- POU Domain, Class 4, Transcription Factor 3
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor Brn-3C".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor Brn-3C".
This graph shows the total number of publications written about "Transcription Factor Brn-3C" by people in this website by year, and whether "Transcription Factor Brn-3C" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor Brn-3C" by people in Profiles.
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Cellular reprogramming with ATOH1, GFI1, and POU4F3 implicate epigenetic changes and cell-cell signaling as obstacles to hair cell regeneration in mature mammals. Elife. 2022 11 29; 11.
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Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan; 129(2):467-77.
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Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9445-50.