Transcription Factor Brn-3A
"Transcription Factor Brn-3A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A POU domain factor that activates GENETIC TRANSCRIPTION of GENES encoding NEUROFILAMENT PROTEINS; alpha internexin; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; and BCL-2 PROTO-ONCOGENE PROTEINS.
| Descriptor ID |
D050819
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| MeSH Number(s) |
D12.776.260.655.625.124 D12.776.930.710.625.500
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| Concept/Terms |
Transcription Factor Brn-3A- Transcription Factor Brn-3A
- Brn-3A, Transcription Factor
- Transcription Factor Brn 3A
- Pou4f1 Transcription Factor
- Transcription Factor, Pou4f1
- Brn-3A Transcription Factor
- Brn 3A Transcription Factor
- Transcription Factor, Brn-3A
- POU Domain, Class 4, Transcription Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor Brn-3A".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor Brn-3A".
This graph shows the total number of publications written about "Transcription Factor Brn-3A" by people in this website by year, and whether "Transcription Factor Brn-3A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factor Brn-3A" by people in Profiles.
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Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Dev Biol. 2012 Apr 15; 364(2):114-27.
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Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. J Neurosci. 2011 Aug 31; 31(35):12413-25.
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Identification of an N-terminal transcriptional activation domain within Brn3b/POU4f2. Differentiation. 2005 Feb; 73(1):18-27.
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The Brn-3a POU family transcription factor stimulates p53 gene expression in human and mouse tumour cells. Neurosci Lett. 2002 Dec 06; 334(1):1-4.
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Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan; 129(2):467-77.
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Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9445-50.
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Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems. Cold Spring Harb Symp Quant Biol. 1997; 62:325-36.
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A novel POU homeodomain gene specifically expressed in cells of the developing mammalian nervous system. Nucleic Acids Res. 1992 Sep 25; 20(18):4919-25.