"Replication Protein A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-stranded DNA-binding protein that is found in EUKARYOTIC CELLS. It is required for DNA REPLICATION; DNA REPAIR; and GENETIC RECOMBINATION.
| Descriptor ID |
D051716
|
| MeSH Number(s) |
D12.776.260.700
|
| Concept/Terms |
Replication Protein A- Replication Protein A
- Single-Strand Binding Protein RP-A
- Single Strand Binding Protein RP A
- Replication Factor A Single-Stranded DNA-Binding Protein
- Replication Factor A Single Stranded DNA Binding Protein
- Replication Factor A
- DNA Replication Factor A
|
Below are MeSH descriptors whose meaning is more general than "Replication Protein A".
Below are MeSH descriptors whose meaning is more specific than "Replication Protein A".
This graph shows the total number of publications written about "Replication Protein A" by people in this website by year, and whether "Replication Protein A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Replication Protein A" by people in Profiles.
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RPA and Rad27 limit templated and inverted insertions at DNA breaks. Nucleic Acids Res. 2025 Jan 07; 53(1).
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Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair. Nat Commun. 2024 Oct 01; 15(1):8511.
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Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2207408119.
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Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue. Blood. 2022 02 17; 139(7):1039-1051.
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Deciphering the mechanism of processive ssDNA digestion by the Dna2-RPA ensemble. Nat Commun. 2022 01 18; 13(1):359.
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Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA. Proc Natl Acad Sci U S A. 2021 06 22; 118(25).
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Homologous recombination enhances radioresistance in hypopharyngeal cancer cell line by targeting DNA damage response. Oral Oncol. 2020 01; 100:104469.
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RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks. Mol Cell. 2015 Oct 15; 60(2):280-93.
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Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. J Cell Biol. 2014 Sep 29; 206(7):877-94.
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DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol Cell. 2014 Jan 09; 53(1):7-18.