Kruppel-Like Transcription Factors
"Kruppel-Like Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of zinc finger transcription factors that share homology with Kruppel protein, Drosophila. They contain a highly conserved seven amino acid spacer sequence in between their ZINC FINGER MOTIFS.
| Descriptor ID |
D051741
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| MeSH Number(s) |
D12.776.260.522 D12.776.930.375
|
| Concept/Terms |
Kruppel-Like Transcription Factors- Kruppel-Like Transcription Factors
- Kruppel Like Transcription Factors
- Transcription Factors, Kruppel-Like
- Kruppel-Like Factors
- Kruppel Like Factors
|
Below are MeSH descriptors whose meaning is more general than "Kruppel-Like Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Kruppel-Like Transcription Factors".
This graph shows the total number of publications written about "Kruppel-Like Transcription Factors" by people in this website by year, and whether "Kruppel-Like Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 3 | 1 | 4 |
| 2010 | 1 | 2 | 3 |
| 2011 | 1 | 1 | 2 |
| 2012 | 4 | 4 | 8 |
| 2013 | 2 | 6 | 8 |
| 2014 | 4 | 7 | 11 |
| 2015 | 4 | 4 | 8 |
| 2016 | 5 | 1 | 6 |
| 2017 | 4 | 2 | 6 |
| 2018 | 1 | 4 | 5 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 2 | 2 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Kruppel-Like Transcription Factors" by people in Profiles.
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Alternative splicing of KLF4 in myeloid cells: implications for cellular plasticity and trained immunity in cancer and inflammatory disease. Front Immunol. 2025; 16:1585528.
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KLF4 enhances transplantation-induced hematopoiesis by inhibiting TLRs and noncanonical NF?B signaling at a steady state. Exp Hematol. 2025 Apr; 144:104730.
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TR? activation confers AT2-to-AT1 cell differentiation and anti-fibrosis during lung repair via KLF2 and CEBPA. Nat Commun. 2024 10 07; 15(1):8672.
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A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling. Nat Cardiovasc Res. 2024 Jul; 3(7):785-798.
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Low NDRG2, regulated by the MYC/MIZ-1 complex and methylation, predicts poor outcomes in DLBCL patients. Ann Hematol. 2024 Aug; 103(8):2877-2892.
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Sirtuin 2 inhibition modulates chromatin landscapes genome-wide to induce senescence in ATRX-deficient malignant glioma. Neuro Oncol. 2024 01 05; 26(1):55-67.
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Sarcomas Harboring EWSR1::PATZ1 Fusions: A Clinicopathologic Study of 17 Cases. Mod Pathol. 2024 Feb; 37(2):100400.
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Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expression. Blood Adv. 2023 03 14; 7(5):712-717.
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EWSR1-PATZ1 Fusion Gene in Ependymoma: A Report of Two Adult Cases and Systematic Review of Literature. JCO Precis Oncol. 2022 12; 6:e2200312.
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A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells. J Cell Biol. 2022 07 04; 221(7).