"Rad51 Recombinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Rec A recombinase found in eukaryotes. Rad51 is involved in DNA REPAIR of double-strand breaks.
| Descriptor ID |
D051135
|
| MeSH Number(s) |
D08.811.739.650.500 D12.776.260.695 D12.776.313.968
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Rad51 Recombinase".
Below are MeSH descriptors whose meaning is more specific than "Rad51 Recombinase".
This graph shows the total number of publications written about "Rad51 Recombinase" by people in this website by year, and whether "Rad51 Recombinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Rad51 Recombinase" by people in Profiles.
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GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer. Nat Commun. 2024 Mar 08; 15(1):2132.
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RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles. Nat Commun. 2023 07 24; 14(1):4445.
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Targeted Inhibition of DNA-PKcs, ATM, ATR, PARP, and Rad51 Modulate Response to X Rays and Protons. Radiat Res. 2022 10 01; 198(4):336-346.
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Autism-Associated Vigilin Depletion Impairs DNA Damage Repair. Mol Cell Biol. 2021 06 23; 41(7):e0008221.
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Rtt105 promotes high-fidelity DNA replication and repair by regulating the single-stranded DNA-binding factor RPA. Proc Natl Acad Sci U S A. 2021 06 22; 118(25).
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Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress. Mol Cancer Ther. 2021 07; 20(7):1257-1269.
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A Rad51-independent pathway promotes single-strand template repair in gene editing. PLoS Genet. 2020 10; 16(10):e1008689.
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Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models. Nat Commun. 2020 07 24; 11(1):3726.
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Cisplatin in Combination with MDM2 Inhibition Downregulates Rad51 Recombinase in a Bimodal Manner to Inhibit Homologous Recombination and Augment Tumor Cell Kill. Mol Pharmacol. 2020 04; 97(4):237-249.
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Loss of SIM2s inhibits RAD51 binding and leads to unresolved replication stress. Breast Cancer Res. 2019 11 27; 21(1):125.