Tumor Suppressor p53-Binding Protein 1
"Tumor Suppressor p53-Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.
| Descriptor ID |
D000071857
|
| MeSH Number(s) |
D12.776.260.805 D12.776.660.235.850 D12.776.664.235.950
|
| Concept/Terms |
Tumor Suppressor p53-Binding Protein 1- Tumor Suppressor p53-Binding Protein 1
- Tumor Suppressor p53 Binding Protein 1
- TP53BP1 Protein
- p202 Protein
- Tumor Protein p53-Binding Protein, 1
- Tumor Protein p53 Binding Protein, 1
- 53BP1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Tumor Suppressor p53-Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Tumor Suppressor p53-Binding Protein 1".
This graph shows the total number of publications written about "Tumor Suppressor p53-Binding Protein 1" by people in this website by year, and whether "Tumor Suppressor p53-Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 5 | 5 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 6 | 6 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 6 | 6 |
| 2011 | 0 | 3 | 3 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 3 | 3 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tumor Suppressor p53-Binding Protein 1" by people in Profiles.
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Ubiquitin-induced RNF168 condensation promotes DNA double-strand break repair. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2322972121.
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Dynamics of the DYNLL1-MRE11 complex regulate DNA end resection and recruitment of Shieldin to DSBs. Nat Struct Mol Biol. 2023 10; 30(10):1456-1467.
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Assessing kinetics and recruitment of DNA repair factors using high content screens. Cell Rep. 2021 12 28; 37(13):110176.
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PRMT5 promotes DNA repair through methylation of 53BP1 and is regulated by Src-mediated phosphorylation. Commun Biol. 2020 08 05; 3(1):428.
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FAM35A associates with REV7 and modulates DNA?damage responses of normal and BRCA1-defective cells. EMBO J. 2018 06 15; 37(12).
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SIRF: Quantitative in situ analysis of protein interactions at DNA replication forks. J Cell Biol. 2018 04 02; 217(4):1521-1536.
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Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein. Cell Death Differ. 2017 12; 24(12):2139-2149.
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Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis. Oncotarget. 2017 Jul 25; 8(30):48671-48687.
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PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice. Cell Death Differ. 2017 12; 24(12):2013-2021.
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Targeting the centriolar replication factor STIL synergizes with DNA damaging agents for treatment of ovarian cancer. Oncotarget. 2017 Apr 18; 8(16):27380-27392.