"Replication Protein C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
| Descriptor ID |
D051818
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| MeSH Number(s) |
D08.811.277.040.013.500.438 D08.811.277.040.025.024.438 D12.776.157.025.750.438 D12.776.260.702
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Replication Protein C".
Below are MeSH descriptors whose meaning is more specific than "Replication Protein C".
This graph shows the total number of publications written about "Replication Protein C" by people in this website by year, and whether "Replication Protein C" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Replication Protein C" by people in Profiles.
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RFC2 may contribute to the pathogenicity of Williams syndrome revealed in a zebrafish model. J Genet Genomics. 2024 Dec; 51(12):1389-1403.
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Biallelic Intronic AAGGG Expansion of RFC1 is Related to Multiple System Atrophy. Ann Neurol. 2020 12; 88(6):1132-1143.
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Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia. Epigenetics. 2013 Mar; 8(3):303-16.
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High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation. J Thorac Oncol. 2012 May; 7(5):833-40.
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Recognition of the ring-opened state of proliferating cell nuclear antigen by replication factor C promotes eukaryotic clamp-loading. J Am Chem Soc. 2010 Jun 02; 132(21):7372-8.
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Cohesin acetylation speeds the replication fork. Nature. 2009 Nov 12; 462(7270):231-4.
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Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC Genomics. 2008 Apr 09; 9:156.
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DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex. J Biol Chem. 2008 Apr 04; 283(14):9071-9.
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A conserved physical and functional interaction between the cell cycle checkpoint clamp loader and DNA ligase I of eukaryotes. J Biol Chem. 2007 Aug 03; 282(31):22721-30.
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The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res. 2007; 35(5):1624-37.