Transcription Factor AP-2

"Transcription Factor AP-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.

Descriptor ID	D050656
MeSH Number(s)	D12.776.260.760 D12.776.930.907
Concept/Terms	Transcription Factor AP-2 Transcription Factor AP-2 AP-2, Transcription Factor Transcription Factor AP 2 Transcription Factor AP2 Enhancer-Binding Protein AP-2 AP-2, Enhancer-Binding Protein Enhancer Binding Protein AP 2 Activator Protein AP-2 AP-2, Activator Protein Activator Protein AP 2 AP-2 Enhancer Binding Protein AP 2 Enhancer Binding Protein Transcription Factor AP-2 epsilon Protein Transcription Factor AP-2 epsilon Protein Transcription Factor AP 2 epsilon Protein Transcription Factor AP-2epsilon AP-2epsilon, Transcription Factor Transcription Factor AP 2epsilon AP-2 epsilon Protein Transcription Factor AP-2 beta Protein Transcription Factor AP-2 beta Protein Transcription Factor AP 2 beta Protein TFAP2B Protein Transcription Factor AP-2beta AP-2beta, Transcription Factor Transcription Factor AP 2beta AP-2 beta Protein AP 2 beta Protein Transcription Factor AP-2 delta Protein Transcription Factor AP-2 delta Protein Transcription Factor AP 2 delta Protein Transcription Factor Ap-2delta Ap-2delta, Transcription Factor Transcription Factor Ap 2delta AP-2delta Protein AP 2delta Protein Transcription Factor AP-2 gamma Protein Transcription Factor AP-2 gamma Protein Transcription Factor AP 2 gamma Protein Transcription Factor AP-2gamma AP-2gamma, Transcription Factor Transcription Factor AP 2gamma AP-2 gamma Protein AP 2 gamma Protein Transcription Factor AP-2 alpha Protein Transcription Factor AP-2 alpha Protein Transcription Factor AP 2 alpha Protein AP-2 alpha Protein AP 2 alpha Protein TFAP2alpha Protein Transcription Factor AP-2alpha AP-2alpha, Transcription Factor Transcription Factor AP 2alpha

Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Transcription Factor AP-2 [D12.776.260.760]
Transcription Factors [D12.776.930]
Transcription Factor AP-2 [D12.776.930.907]

Below are MeSH descriptors whose meaning is related to "Transcription Factor AP-2".

Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Transcription Factor AP-2" by people in this website by year, and whether "Transcription Factor AP-2" was a major or minor topic of these publications.

Bar chart showing 50 publications over 23 distinct years, with a maximum of 6 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	2	2
1996	0	4	4
1997	0	1	1
1998	0	2	2
1999	0	2	2
2001	0	5	5
2002	0	1	1
2003	0	4	4
2004	0	1	1
2005	2	2	4
2006	2	0	2
2007	4	2	6
2008	0	1	1
2009	1	1	2
2010	2	2	4
2011	1	1	2
2012	0	1	1
2013	1	0	1
2015	0	1	1
2017	0	1	1
2018	1	0	1
2019	1	0	1
2020	0	1	1

Below are the most recent publications written about "Transcription Factor AP-2" by people in Profiles.

Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Commun Biol. 2020 04 07; 3(1):165.

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The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation. Hum Mol Genet. 2019 05 15; 28(10):1726-1737.

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The transcription factor Tfap2e/AP-2e plays a pivotal role in maintaining the identity of basal vomeronasal sensory neurons. Dev Biol. 2018 09 01; 441(1):67-82.

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Impact of selective serotonin reuptake inhibitors on neural crest stem cell formation. Toxicol Lett. 2017 Nov 05; 281:20-25.

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TransCONFIRM: Identification of a Genetic Signature of Response to Fulvestrant in Advanced Hormone Receptor-Positive Breast Cancer. Clin Cancer Res. 2016 Dec 01; 22(23):5755-5764.

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Integrative Analysis Reveals Regulatory Programs in Endometriosis. Reprod Sci. 2015 Sep; 22(9):1060-72.

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Estrogen receptor alpha: molecular mechanisms and emerging insights. J Cell Biochem. 2013 Oct; 114(10):2203-8.

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MicroRNA-17-92, a direct Ap-2a transcriptional target, modulates T-box factor activity in orofacial clefting. PLoS Genet. 2013; 9(9):e1003785.

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Driving transcriptional regulators in melanoma metastasis. Cancer Metastasis Rev. 2012 Dec; 31(3-4):621-32.

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Activating enhancer-binding protein-2? nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection. Ann Thorac Surg. 2011 Sep; 92(3):1044-50.

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