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Stephen Matthew Farmer

TitlePostdoc Fellows and Associates
InstitutionBaylor College of Medicine
DepartmentPostDoc
Address
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    K00NS141400     (FARMER, STEPHEN M)Sep 18, 2024 - Aug 31, 2030
    NIH
    The role of Huntingtin in endolysosomal trafficking and Huntington's disease pathogenesis
    Role: Principal Investigator
    F99NS141400     (FARMER, STEPHEN M)Sep 18, 2024 - Aug 31, 2026
    NIH
    The role of Huntingtin in endolysosomal trafficking and Huntington's disease pathogenesis
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wheeler EC, Yang R, Farmer SM, Zhang S, Zhang N, An Z, Tong Q. A genetic tool targeting brain GPR75. bioRxiv. 2026 Jun 02. PMID: 42282582; PMCID: PMC13251911.
      Citations:    
    2. Daquinag AC, Ghosh SC, AghaAmiri S, Farmer SM, Zhang S, Vargas SH, Ramesh AK, An Z, Azhdarinia A, Kolonin MG. Fibulin-4 expressed in metastatic breast cancer is a target of peptide-based imaging probes and experimental therapeutics. Mol Ther Oncol. 2026 Jun 18; 34(2):201207. PMID: 42124952; PMCID: PMC13158586.
      Citations:    
    3. Zhao X, Erhardt S, Tang L, Chen X, Farmer SM, Cheng Z, Chen W, Lu EZ, Sung K, Tsai CR, Zheng M, Zhang S, Liu Y, Wang J, Li M, Martin JF, Wang J. ERK-Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells. Adv Sci (Weinh). 2026 Jul; 13(37):e11484. PMID: 41961483; PMCID: PMC13334658.
      Citations:    
    4. Farmer SM, Xu S, Yu Y, Ye X, Yang H, Cai J, Rios B, Lin WW, Covarrubias D, Chuong V, Ye L, Zylberberg G, Wang C, Furr-Stimming E, Tong Q, Kanca O, Bellen HJ, Moore TI, Zhang S. Rab4 spatially and functionally converges with Rab7 in the degradative endolysosomal network. Mol Biol Cell. 2026 Mar 01; 37(3):ar18. PMID: 41537736; PMCID: PMC12911854.
      Citations:    Fields:    Translation:AnimalsCells
    5. Rios B, Xu S, Farmer SM, Ye X, Ye L, Morano KA, Zhang SA. Functional Characterization of Hsp110 in Drosophila Reveals its Essential and Dosage-Sensitive Role in Nervous System Integrity. bioRxiv. 2025 Nov 19. PMID: 41332560; PMCID: PMC12667898.
      Citations:    
    6. Daquinag AC, AghaAmiri S, Farmer SM, Zhang S, Ghosh SC, Vargas SH, Ramesh AK, An Z, Azhdarinia A, Kolonin MG. Fibulin-4 is highly expressed in metastatic breast cancer and can serve as a target of peptide-based imaging probes and experimental therapeutics. bioRxiv. 2025 Jun 19. PMID: 40611893; PMCID: PMC12224531.
      Citations:    
    7. Farmer SM, Solbach A, Xu S, Rios B, Ye X, Gao A, Covarrubias D, Yu Y, Ye L, Chuong V, Furr Stimming E, Zhao H, Zhang S. Structural-functional analyses of the huntingtin/HAP40 complex in Drosophila and humans. J Biomol Struct Dyn. 2026 04; 44(6):3163-3178. PMID: 40091796; PMCID: PMC12353482.
      Citations:    
    8. Yu Y, Chen D, Farmer SM, Xu S, Rios B, Solbach A, Ye X, Ye L, Zhang S. Endolysosomal trafficking controls yolk granule biogenesis in vitellogenic Drosophila oocytes. PLoS Genet. 2024 02; 20(2):e1011152. PMID: 38315726; PMCID: PMC10898735.
      Citations:    
    9. Cho HJ, Gurbuz F, Stamou M, Kotan LD, Farmer SM, Can S, Tompkins MF, Mammadova J, Altincik SA, Gokce C, Catli G, Bugrul F, Bartlett K, Turan I, Balasubramanian R, Yuksel B, Seminara SB, Wray S, Topaloglu AK. POU6F2 mutation in humans with pubertal failure alters GnRH transcript expression. Front Endocrinol (Lausanne). 2023; 14:1203542. PMID: 37600690; PMCID: PMC10436210.
      Citations:    
    10. Xu S, Li G, Ye X, Chen D, Chen Z, Xu Z, Daniele M, Tambone S, Ceccacci A, Tomei L, Ye L, Yu Y, Solbach A, Farmer SM, Stimming EF, McAllister G, Marchionini DM, Zhang S. HAP40 is a conserved central regulator of Huntingtin and a potential modulator of Huntington's disease pathogenesis. PLoS Genet. 2022 07; 18(7):e1010302. PMID: 35853002; PMCID: PMC9295956.
      Citations:    
    11. Welch BA, Cho HJ, Ucakturk SA, Farmer SM, Cetinkaya S, Abaci A, Akkus G, Simsek E, Kotan LD, Turan I, Gurbuz F, Yuksel B, Wray S, Topaloglu AK. PLXNB1 mutations in the etiology of idiopathic hypogonadotropic hypogonadism. J Neuroendocrinol. 2022 04; 34(4):e13103. PMID: 35170806; PMCID: PMC11370887.
      Citations:    
    12. Shan Y, Farmer SM, Wray S. Drebrin regulates cytoskeleton dynamics in migrating neurons through interaction with CXCR4. Proc Natl Acad Sci U S A. 2021 01 19; 118(3). PMID: 33414275; PMCID: PMC7826346.
      Citations:    
    13. Farmer SM, Andl CD. Computational modeling of transforming growth factor ? and activin a receptor complex formation in the context of promiscuous signaling regulation. J Biomol Struct Dyn. 2021 09; 39(14):5166-5181. PMID: 32597324.
      Citations:    
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