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KEITH WEBSTER

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Ophthalmology
Address6501 Fannin St
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Huang C, Kaur A, Ji L, Tian H, Webster KA, Li W. Suppression of matrigel-induced choroidal neovascularization by AAV delivery of a novel anti-Scg3 antibody. Gene Ther. 2024 Nov; 31(11-12):587-593. PMID: 39333408.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Huang C, Waduge P, Kaur A, Tian H, Weng CY, Stout JT, Pang IH, Webster KA, Li W. Optimal Humanized Scg3-Neutralizing Antibodies for Anti-Angiogenic Therapy of Diabetic Retinopathy. Int J Mol Sci. 2024 Sep 01; 25(17). PMID: 39273454; PMCID: PMC11394726.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Fu Y, Zhang Z, Webster KA, Paulus YM. Treatment Strategies for Anti-VEGF Resistance in Neovascular Age-Related Macular Degeneration by Targeting Arteriolar Choroidal Neovascularization. Biomolecules. 2024 Feb 21; 14(3). PMID: 38540673; PMCID: PMC10968528.
      Citations: 3     Fields:    Translation:HumansAnimals
    4. Lalwani RC, Volmar CH, Wahlestedt C, Webster KA, Shehadeh LA. Contextualizing the Role of Osteopontin in the Inflammatory Responses of Alzheimer's Disease. Biomedicines. 2023 Dec 06; 11(12). PMID: 38137453; PMCID: PMC10741223.
      Citations: 2     
    5. Huang C, Ji L, Kaur A, Tian H, Waduge P, Webster KA, Li W. Anti-Scg3 Gene Therapy to Treat Choroidal Neovascularization in Mice. Biomedicines. 2023 Jul 06; 11(7). PMID: 37509549; PMCID: PMC10377229.
      Citations:    
    6. Ji L, Waduge P, Wu Y, Huang C, Kaur A, Oliveira P, Tian H, Zhang J, Stout JT, Weng CY, Webster KA, Li W. Secretogranin III Selectively Promotes Vascular Leakage in the Deep Vascular Plexus of Diabetic Retinopathy. Int J Mol Sci. 2023 Jun 23; 24(13). PMID: 37445707; PMCID: PMC10341987.
      Citations:    Fields:    Translation:AnimalsCells
    7. Waduge P, Tian H, Webster KA, Li W. Profiling disease-selective drug targets: From proteomics to ligandomics. Drug Discov Today. 2023 03; 28(3):103430. PMID: 36343915; PMCID: PMC9974940.
      Citations: 1     Fields:    
    8. Irion CI, Williams M, Capcha JC, Eisenberg T, Lambert G, Takeuchi LM, Seo G, Yousefi K, Kanashiro-Takeuchi R, Webster KA, Young KC, Hare JM, Shehadeh LA. Col4a3-/- Mice on Balb/C Background Have Less Severe Cardiorespiratory Phenotype and SGLT2 Over-Expression Compared to 129x1/SvJ and C57Bl/6 Backgrounds. Int J Mol Sci. 2022 Jun 15; 23(12). PMID: 35743114; PMCID: PMC9223785.
      Citations:    Fields:    Translation:Animals
    9. Dai C, Tian H, Bhatt A, Su G, Webster KA, Li W. Safety and Efficacy of Systemic Anti-Scg3 Therapy to Treat Oxygen-Induced Retinopathy. Front Biosci (Landmark Ed). 2022 04 19; 27(4):130. PMID: 35468689; PMCID: PMC9201993.
      Citations:    Fields:    Translation:HumansAnimals
    10. Dai C, Waduge P, Ji L, Huang C, He Y, Tian H, Zuniga-Sanchez E, Bhatt A, Pang IH, Su G, Webster KA, Li W. Secretogranin III stringently regulates pathological but not physiological angiogenesis in oxygen-induced retinopathy. Cell Mol Life Sci. 2022 Jan 10; 79(1):63. PMID: 35006382; PMCID: PMC9007175.
      Citations: 3     Fields:    Translation:Animals
    11. Ji L, Waduge P, Hao L, Kaur A, Wan W, Wu Y, Tian H, Zhang J, Webster KA, Li W. Selectively targeting disease-restricted secretogranin III to alleviate choroidal neovascularization. FASEB J. 2022 01; 36(1):e22106. PMID: 34918375; PMCID: PMC8694659.
      Citations: 3     Fields:    Translation:AnimalsCells
    12. He Y, Tian H, Dai C, Wen R, Li X, Webster KA, Li W. Optimal Efficacy and Safety of Humanized Anti-Scg3 Antibody to Alleviate Oxygen-Induced Retinopathy. Int J Mol Sci. 2021 Dec 29; 23(1). PMID: 35008775; PMCID: PMC8745183.
      Citations:    Fields:    Translation:HumansAnimalsCells
    13. Ji L, Tian H, Webster KA, Li W. Neurovascular regulation in diabetic retinopathy and emerging therapies. Cell Mol Life Sci. 2021 Aug; 78(16):5977-5985. PMID: 34230991; PMCID: PMC8602033.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    14. Dai C, Webster KA, Bhatt A, Tian H, Su G, Li W. Concurrent Physiological and Pathological Angiogenesis in Retinopathy of Prematurity and Emerging Therapies. Int J Mol Sci. 2021 May 01; 22(9). PMID: 34062733; PMCID: PMC8124946.
      Citations: 7     Fields:    Translation:HumansAnimals
    15. Yousefi K, Irion CI, Takeuchi LM, Ding W, Lambert G, Eisenberg T, Sukkar S, Granzier HL, Methawasin M, Lee DI, Hahn VS, Kass DA, Hatzistergos KE, Hare JM, Webster KA, Shehadeh LA. Osteopontin Promotes Left Ventricular Diastolic Dysfunction Through a Mitochondrial Pathway. J Am Coll Cardiol. 2019 06 04; 73(21):2705-2718. PMID: 31146816; PMCID: PMC6546303.
      Citations:    
    16. Li W, Webster KA, LeBlanc ME, Tian H. Secretogranin III: a diabetic retinopathy-selective angiogenic factor. Cell Mol Life Sci. 2018 02; 75(4):635-647. PMID: 28856381; PMCID: PMC5771826.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    17. Wang W, LeBlanc ME, Chen X, Chen P, Ji Y, Brewer M, Tian H, Spring SR, Webster KA, Li W. Pathogenic role and therapeutic potential of pleiotrophin in mouse models of ocular vascular disease. Angiogenesis. 2017 Nov; 20(4):479-492. PMID: 28447229; PMCID: PMC5658272.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    18. Boden J, Lassance-Soares RM, Wang H, Wei Y, Spiga MG, Adi J, Layman H, Yu H, Vazquez-Padron RI, Andreopoulos F, Webster KA. Vascular Regeneration in Ischemic Hindlimb by Adeno-Associated Virus Expressing Conditionally Silenced Vascular Endothelial Growth Factor. J Am Heart Assoc. 2016 05 26; 5(6). PMID: 27231018; PMCID: PMC4937238.
      Citations:    
    19. Hu X, Chen P, Wu Y, Wang K, Xu Y, Chen H, Zhang L, Wu R, Webster KA, Yu H, Zhu W, Wang J. MiR-211/STAT5A Signaling Modulates Migration of Mesenchymal Stem Cells to Improve its Therapeutic Efficacy. Stem Cells. 2016 07; 34(7):1846-58. PMID: 27145179; PMCID: PMC5096301.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    20. Ma Q, Xia X, Tao Q, Lu K, Shen J, Xu Q, Hu X, Tang Y, Block NL, Webster KA, Schally AV, Wang J, Yu H. Profound Actions of an Agonist of Growth Hormone-Releasing Hormone on Angiogenic Therapy by Mesenchymal Stem Cells. Arterioscler Thromb Vasc Biol. 2016 Apr; 36(4):663-672. PMID: 26868211; PMCID: PMC4808467.
      Citations:    
    21. Hu X, Zhang L, Jin J, Zhu W, Xu Y, Wu Y, Wang Y, Chen H, Webster KA, Chen H, Yu H, Wang J. Heparanase released from mesenchymal stem cells activates integrin beta1/HIF-2alpha/Flk-1 signaling and promotes endothelial cell migration and angiogenesis. Stem Cells. 2015 Jun; 33(6):1850-1862. PMID: 25754303; PMCID: PMC5108061.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    22. LeBlanc ME, Wang W, Caberoy NB, Chen X, Guo F, Alvarado G, Shen C, Wang F, Wang H, Chen R, Liu ZJ, Webster K, Li W. Hepatoma-derived growth factor-related protein-3 is a novel angiogenic factor. PLoS One. 2015; 10(5):e0127904. PMID: 25996149; PMCID: PMC4440747.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    23. Hu X, Wu R, Jiang Z, Wang L, Chen P, Zhang L, Yang L, Wu Y, Chen H, Chen H, Xu Y, Zhou Y, Huang X, Webster KA, Yu H, Wang J. Leptin signaling is required for augmented therapeutic properties of mesenchymal stem cells conferred by hypoxia preconditioning. Stem Cells. 2014 Oct; 32(10):2702-13. PMID: 24989835; PMCID: PMC5096299.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    24. Jiang Z, Hu X, Yu H, Xu Y, Wang L, Chen H, Chen H, Wu R, Zhang Z, Xiang C, Webster KA, Wang JA. Human endometrial stem cells confer enhanced myocardial salvage and regeneration by paracrine mechanisms. J Cell Mol Med. 2013 Oct; 17(10):1247-60. PMID: 23837896; PMCID: PMC3843975.
      Citations:    
    25. Zhou MS, Chadipiralla K, Mendez AJ, Jaimes EA, Silverstein RL, Webster K, Raij L. Nicotine potentiates proatherogenic effects of oxLDL by stimulating and upregulating macrophage CD36 signaling. Am J Physiol Heart Circ Physiol. 2013 Aug 15; 305(4):H563-74. PMID: 23748423; PMCID: PMC3891251.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    26. Shao H, Xu Q, Wu Q, Ma Q, Salgueiro L, Wang J, Eton D, Webster KA, Yu H. Defective CXCR4 expression in aged bone marrow cells impairs vascular regeneration. J Cell Mol Med. 2011 Oct; 15(10):2046-56. PMID: 21143386; PMCID: PMC3076550.
      Citations: 18     Fields:    Translation:AnimalsCells
    27. Song X, Ma Q, Liu X, Seo P, Herderick E, Webster K, Goldschmidt-Clermont PJ, Seo D. Will periodic intravenous injections of conditioned bone marrow cells effectively reduce atherosclerosis? Antioxid Redox Signal. 2012 Jan 01; 16(1):85-91. PMID: 21740335; PMCID: PMC3218380.
      Citations: 3     Fields:    Translation:Animals
    28. Dougherty CJ, Smith GW, Dorey CK, Prentice HM, Webster KA, Blanks JC. Robust hypoxia-selective regulation of a retinal pigment epithelium-specific adeno-associated virus vector. Mol Vis. 2008 Mar 07; 14:471-80. PMID: 18334957; PMCID: PMC2268848.
      Citations:    
    29. Cho HM, Rosenblatt JD, Kang YS, Iruela-Arispe ML, Morrison SL, Penichet ML, Kwon YG, Kim TW, Webster KA, Nechustan H, Shin SU. Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein. Mol Cancer Ther. 2005 Jun; 4(6):956-67. PMID: 15956253.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    30. Gounis MJ, Spiga MG, Graham RM, Wilson A, Haliko S, Lieber BB, Wakhloo AK, Webster KA. Angiogenesis is confined to the transient period of VEGF expression that follows adenoviral gene delivery to ischemic muscle. Gene Ther. 2005 May; 12(9):762-71. PMID: 15772688.
      Citations:    
    31. Dougherty CJ, Kubasiak LA, Frazier DP, Li H, Xiong WC, Bishopric NH, Webster KA. Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation. FASEB J. 2004 Jul; 18(10):1060-70. PMID: 15226266.
      Citations: 40     Fields:    Translation:AnimalsCells
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