"Immediate-Early Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.
| Descriptor ID |
D017874
|
| MeSH Number(s) |
D12.776.460 D12.776.964.925.968
|
| Concept/Terms |
Immediate-Early Proteins- Immediate-Early Proteins
- Immediate Early Proteins
- Proteins, Immediate-Early
- Proteins, Immediate Early
|
Below are MeSH descriptors whose meaning is more general than "Immediate-Early Proteins".
Below are MeSH descriptors whose meaning is more specific than "Immediate-Early Proteins".
This graph shows the total number of publications written about "Immediate-Early Proteins" by people in this website by year, and whether "Immediate-Early Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Immediate-Early Proteins" by people in Profiles.
-
Increased IFRD1 Expression in Human Colon Cancers Predicts Reduced Patient Survival. Dig Dis Sci. 2017 12; 62(12):3460-3467.
-
Serum Glucocorticoid-Regulated Kinase 1 Blocks CKD-Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3. J Am Soc Nephrol. 2016 09; 27(9):2797-808.
-
Estrogen receptor ? regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation. Fertil Steril. 2016 05; 105(5):1266-1273.
-
p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer. Breast Cancer Res. 2016 Jan 27; 18(1):13.
-
IFRD1 gene polymorphisms are associated with nasal polyposis in cystic fibrosis patients. Rhinology. 2015 12; 53(4):359-64.
-
Is CMV a target in pediatric glioblastoma? Expression of CMV proteins, pp65 and IE1-72 and CMV nucleic acids in a cohort of pediatric glioblastoma patients. J Neurooncol. 2015 Nov; 125(2):307-15.
-
Raloxifene inhibits growth of RT4 urothelial carcinoma cells via estrogen receptor-dependent induction of apoptosis and inhibition of proliferation. Horm Cancer. 2013 Feb; 4(1):24-35.
-
Serum-glucocorticoid regulated kinase 1 regulates alternatively activated macrophage polarization contributing to angiotensin II-induced inflammation and cardiac fibrosis. Arterioscler Thromb Vasc Biol. 2012 Jul; 32(7):1675-86.
-
Human cytomegalovirus infection causes degradation of Sp100 proteins that suppress viral gene expression. J Virol. 2011 Nov; 85(22):11928-37.
-
EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011; 28(1):137-46.