"Aconitate Hydratase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the reversible hydration of cis-aconitate to yield citrate or isocitrate. It is one of the citric acid cycle enzymes. EC 4.2.1.3.
| Descriptor ID |
D000154
|
| MeSH Number(s) |
D08.811.520.241.300.050
|
| Concept/Terms |
Aconitate Hydratase- Aconitate Hydratase
- Hydratase, Aconitate
- Citrate Hydrolyase
- Hydrolyase, Citrate
- Isocitrate Hydro-Lyase
- Hydro-Lyase, Isocitrate
- Isocitrate Hydro Lyase
- Aconitase
- Citrate Hydro-Lyase
- Citrate Hydro Lyase
- Hydro-Lyase, Citrate
|
Below are MeSH descriptors whose meaning is more general than "Aconitate Hydratase".
Below are MeSH descriptors whose meaning is more specific than "Aconitate Hydratase".
This graph shows the total number of publications written about "Aconitate Hydratase" by people in this website by year, and whether "Aconitate Hydratase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Aconitate Hydratase" by people in Profiles.
-
Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone. Cancer Res. 2021 01 01; 81(1):50-63.
-
Recessive ACO2 variants as a cause of isolated ophthalmologic phenotypes. Am J Med Genet A. 2020 08; 182(8):1960-1966.
-
Functional cellular analyses reveal energy metabolism defect and mitochondrial DNA depletion in a case of mitochondrial aconitase deficiency. Mol Genet Metab. 2016 May; 118(1):28-34.
-
4-hydroxynonenal regulates mitochondrial function in human small airway epithelial cells. Oncotarget. 2015 Dec 08; 6(39):41508-21.
-
TORC1 Inhibition by Rapamycin Promotes Antioxidant Defences in a Drosophila Model of Friedreich's Ataxia. PLoS One. 2015; 10(7):e0132376.
-
MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging. Aging Cell. 2011 Jun; 10(3):493-505.
-
Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity. Am J Physiol Cell Physiol. 2009 Dec; 297(6):C1520-32.
-
Genetic or pharmacologic amplification of nrf2 signaling inhibits acute inflammatory liver injury in mice. Toxicol Sci. 2008 Jul; 104(1):218-27.
-
Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem. 2004 Nov 19; 279(47):49064-73.
-
Inhibition of aconitase in astrocytes increases the sensitivity to chemical convulsants. Epilepsy Res. 2004 Jun; 60(1):41-52.