Phosphopyruvate Hydratase
"Phosphopyruvate Hydratase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hydro-lyase that catalyzes the dehydration of 2-phosphoglycerate to form PHOSPHOENOLPYRUVATE. Several different isoforms of this enzyme exist, each with its own tissue specificity.
| Descriptor ID |
D010751
|
| MeSH Number(s) |
D08.811.520.241.300.500
|
| Concept/Terms |
Phosphopyruvate Hydratase- Phosphopyruvate Hydratase
- Hydratase, Phosphopyruvate
- 2-Phospho-D-Glycerate Hydrolase
- 2 Phospho D Glycerate Hydrolase
- Enolase
- 2-Phospho-D-Glycerate Hydro-Lyase
- 2 Phospho D Glycerate Hydro Lyase
- Hydro-Lyase, 2-Phospho-D-Glycerate
- 2-Phosphoglycerate Dehydratase
- 2 Phosphoglycerate Dehydratase
- Dehydratase, 2-Phosphoglycerate
gamma-Enolase- gamma-Enolase
- gamma Enolase
- Nervous System-Specific Enolase
- Enolase, Nervous System-Specific
- Nervous System Specific Enolase
- System-Specific Enolase, Nervous
- Neuron-Specific Enolase
- Enolase, Neuron-Specific
- Neuron Specific Enolase
- Enolase 2
alpha-Enolase- alpha-Enolase
- alpha Enolase
- Non-Neuronal Enolase
- Enolase, Non-Neuronal
- Non Neuronal Enolase
beta-Enolase- beta-Enolase
- beta Enolase
- Muscle-Specific Enolase
- Enolase, Muscle-Specific
- Muscle Specific Enolase
- Enolase 3
|
Below are MeSH descriptors whose meaning is more general than "Phosphopyruvate Hydratase".
Below are MeSH descriptors whose meaning is more specific than "Phosphopyruvate Hydratase".
This graph shows the total number of publications written about "Phosphopyruvate Hydratase" by people in this website by year, and whether "Phosphopyruvate Hydratase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 3 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phosphopyruvate Hydratase" by people in Profiles.
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Enolase inhibitors as therapeutic leads for Naegleria fowleri infection. PLoS Pathog. 2024 Aug; 20(8):e1012412.
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Role of neuron-specific enolase as a prognostic marker in pediatric cardiac arrest. Am J Emerg Med. 2024 02; 76:258-260.
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Prodrugs of a 1-Hydroxy-2-oxopiperidin-3-yl Phosphonate Enolase Inhibitor for the Treatment of ENO1-Deleted Cancers. J Med Chem. 2022 10 27; 65(20):13813-13832.
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An enolase inhibitor for the targeted treatment of ENO1-deleted cancers. Nat Metab. 2020 12; 2(12):1413-1426.
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The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues. Molecules. 2019 Jul 09; 24(13).
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Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells. Sci Immunol. 2019 01 25; 4(31).
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Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. Nat Commun. 2018 12 17; 9(1):5339.
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Genetic Architecture of Primary Open-Angle Glaucoma in Individuals of African Descent: The African Descent and Glaucoma Evaluation Study III. Ophthalmology. 2019 01; 126(1):38-48.
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Multimodal Outcome Prognostication After Cardiac Arrest and Targeted Temperature Management: Analysis at 36??C. Neurocrit Care. 2018 02; 28(1):104-109.
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Unique findings of subependymal giant cell astrocytoma within cortical tubers in patients with tuberous sclerosis complex: a histopathological evaluation. Childs Nerv Syst. 2017 Apr; 33(4):601-607.